Invitrogen™
TESTED APPLICATIONS | DILUTION |
---|---|
Flow Cytometry (Flow) | Assay Dependent |
Species reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Clone | 581 |
Immunogen | Human CD34. |
Form | Liquid |
Concentration | 0.5 mg/ml |
Purification | purified |
Storage buffer | PBS, pH 7.2 |
Contains | 0.09% sodium azide |
Storage conditions | 4° C |
CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD34 antigen; hematopoietic progenitor cell antigen CD34; Mucosialin; RP11-328D5.2
Gene Aliases: RP11-328D5.2
UniProt ID: (Human) P28906
Entrez Gene ID: (Human) 947
Molecular Function:
Cell adhesion molecule
Miscellaneous function
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