|Tested species reactivity||Human|
|Published species reactivity||Rat, Not Applicable|
|Host / Isotype||Mouse / IgM|
|Immunogen||Human tonsil and peripheral blood mononuclear cells.|
|Storage buffer||PBS with 1mg/ml BSA|
|Contains||10mM sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||10 µL/Test|
|Immunohistochemistry (IHC)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
CD36 is a cell surface class B scavenger receptor. CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signaling and adapter molecules. CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It may function as a cell adhesion molecule and directly mediates cyto- adherence of Plasmodium falciparum parasitized erythrocytes. CD36 binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Trauma-hemorrhagic shock induces a CD36-dependent RBC endothelial-adhesive phenotype.
AHS3608 was used in flow cytometry and immunocytochemistry to test if trauma-hemorrhage induces RBC-endothelial cell adhesion
|Deitch EA,Condon M,Feketeova E,Machiedo GW,Mason L,Vinluan GM,Alli VA,Neal MD,Tomaio JN,Fishman JE,Durán WN,Spolarics Z||Critical care medicine (42:e200)||2014|
|Not Applicable||10 µg/ml||
Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways.
AHS3608 was used in flow cytometry to characterize HIV interactions with dendritic cells
|Blauvelt A,Asada H,Saville MW,Klaus-Kovtun V,Altman DJ,Yarchoan R,Katz SI||The Journal of clinical investigation (100:2043)||1997|