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Immunofluorescent analysis of CD37/Tspan-26 showing staining in the cell membrane of Raji cells. Raji cells were fixed in 4% paraformaldehyde at RT for 15 min and stained using a CD37/Tspan-26 polyclonal antibody (Product # PA5-31332) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10µm.
|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 12 and 281 of Human CD37|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31332 targets CD37 in IF and ICC applications and shows reactivity with Human samples.
The PA5-31332 immunogen is recombinant fragment corresponding to a region within amino acids 12 and 281 of Human CD37.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD37 antigen; cell differentiation antigen 37; GP52-40; leukocyte antigen CD37; leukocyte surface antigen CD37; tetraspanin-26; tspan-26; TSPAN26
CD37; GP52-40; TSPAN26