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      CD38 Monoclonal Antibody (HIT2), APC-Cyanine5.5

      See 53 other CD38 antibodies ›
      CD38 Monoclonal Antibody, APC-Cyanine5.5 conjugate for Flow

      Catalog#: MHCD3819 Invitrogen

      Catalog # Size Price (USD) Qty Datasheet
      MHCD3819 0.5 ml
      356.00
      Please enter a quantity in the range of 1 to 199.
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      Product Details

      Bioinformatics

      Documents
      Details
      Tested species reactivity Human
      Host / Isotype Mouse / IgG1
      Class Monoclonal
      Type Antibody
      Clone HIT2
      Immunogen Human CD38
      Conjugate APC-Cyanine5.5
      Form Liquid
      Purification purified
      Storage buffer PBS with BSA, sucrose
      Contains 0.1% sodium azide
      Storage Conditions 4° C, store in dark
      Tested Applications Dilution *
      Flow Cytometry (Flow) Assay-Dependent

      * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

      Background/Target Information

      CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration.

      Analyte Specific Reagent

      Bioinformatics

      Protein Aliases:

      2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADPRC 1; cADPr hydrolase 1; CD38; CD38 antigen (p45); CD38 antigen p45; cluster of differentiation 38; Cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; NAD(+) nucleosidase; NAD+ nucleosidase; T10

      Gene Aliases:

      ADPRC 1; ADPRC1; CD38

      UniProt ID:

      (Human) P28907

      Entrez Gene ID:

      (Human) 952

      Molecular Function:

      cyclase glycosidase hydrolase lyase

      Function(s) Process(es)

      Documents

      Material safety data sheets (MSDS)

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