|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Human CD3 delta|
|Storage buffer||PBS with 4mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 3 publications below|
R-phycoerythrin (PE) is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing an exceptional quantum yields and molar extinction coefficients.
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
Class 2 Device
Zoster Vaccination Increases the Breadth of CD4+ T Cells Responsive to Varicella Zoster Virus.
MHCD0304 was used in flow cytometry to measure the memory CD4(+) T-cell responses to each varicella zoster virus protein at baseline and after zoster vaccination.
|Laing KJ,Russell RM,Dong L,Schmid DS,Stern M,Magaret A,Haas JG,Johnston C,Wald A,Koelle DM||The Journal of infectious diseases (212:1022)||2015|
Preclinical evaluation of carcinoembryonic cell adhesion molecule (CEACAM) 6 as potential therapy target for pancreatic adenocarcinoma.
MHCD0304 was used in flow cytometry to investigate targeting CEACAM6 for treatment of pancreatic adenocarcinomas.
|Strickland LA,Ross J,Williams S,Ross S,Romero M,Spencer S,Erickson R,Sutcliffe J,Verbeke C,Polakis P,van Bruggen N,Koeppen H||The Journal of pathology (218:380)||2009|
Investigation of human spleen dendritic cell phenotype and distribution reveals evidence of in vivo activation in a subset of organ donors.
MHCD0304 was used in flow cytometry to characterize human splenic dendritic cells.
|McIlroy D,Troadec C,Grassi F,Samri A,Barrou B,Autran B,Debré P,Feuillard J,Hosmalin A||Blood (97:3470)||2001|