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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Human CD3 delta|
|Storage buffer||PBS with 10% sucrose, BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The TRI-COLOR® conjugate is a tandem R-phycoerythrin (PE)-Cy5® conjugate that permits simultaneous multicolor labeling and detection of multiple targets with excitation by a single excitation source-the 488 nm line of the argon-ion laser.
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
Class 2 Device
Intermediate DNA methylation is a conserved signature of genome regulation.
MHCD0306 was used in flow cytometry to show that intermediate DNA methylation is a conserved signature of gene regulation and exon usage
|Elliott G,Hong C,Xing X,Zhou X,Li D,Coarfa C,Bell RJ,Maire CL,Ligon KL,Sigaroudinia M,Gascard P,Tlsty TD,Harris RA,Schalkwyk LC,Bilenky M,Mill J,Farnham PJ,Kellis M,Marra MA,Milosavljevic A,Hirst M,Stormo GD,Wang T,Costello JF||Nature communications (6:null)||2015|
Immunological/virological peripheral blood biomarkers and distinct patterns of sleeping quality in chronic hepatitis C patients.
MHCD0306 was used in flow cytometry to identify immunological/virological biomarkers associated with sleep quality in patients with chronic hepatitis C.
|de Almeida CM,de Lima TA,Castro DB,Torres KL,da Silva Braga W,Peruhype-Magalhães V,Teixeira-Carvalho A,Martins-Filho OA,Malheiro A||Scandinavian journal of immunology (73:486)||2011|
Perturbations in eosinophil homeostasis following treatment of lymphatic filariasis.
MHCD0306 was used in flow cytometry to study perturbations in eosinophil homeostasis following treatment of lymphatic filariasis.
|Gopinath R,Hanna LE,Kumaraswami V,Perumal V,Kavitha V,Vijayasekaran V,Nutman TB||Infection and immunity (68:93)||2000|
Flow cytometry in the bone marrow staging of mature B-cell neoplasms.
MHCD0306 was used in flow cytometry to ask if flow cytometry can be used for the detection of bone marrow involvement in the different types of B-cell malignant neoplasms.
|Stacchini A,Demurtas A,Godio L,Martini G,Antinoro V,Palestro G||Cytometry. Part B, Clinical cytometry (54:10)||2003|
Chemokine receptor CCR4 on CD4+ T cells in juvenile rheumatoid arthritis synovial fluid defines a subset of cells with increased IL-4:IFN-gamma mRNA ratios.
MHCD0306 was used in flow cytometry to elucidate the mechanisms that promote recruitment and survival of T cells within the pediatric inflamed joint.
|Thompson SD,Luyrink LK,Graham TB,Tsoras M,Ryan M,Passo MH,Glass DN||Journal of immunology (Baltimore, Md. : 1950) (166:6899)||2001|
Multiple co-stimulatory signals are required for triggering proliferation of T cells from human secondary lymphoid tissue.
MHCD0306 was used in flow cytometry to compare the immune responses of T cells isolated from human secondary lymphoid organs and peripheral blood.
|Agrawal SG,Marquet J,Plumas J,Rouard H,Delfau-Larue MH,Gaulard P,Boumsell L,Reyes F,Bensussan A,Farcet JP||International immunology (13:441)||2001|
Down regulation of CD4 expression following isolation and culture of human monocytes.
MHCD0306 was used in flow cytometry to identify factors that down regulate CD4 on cultured monocytes.
|Graziani-Bowering GM,Filion LG||Clinical and diagnostic laboratory immunology (7:182)||2000|
Blister fluid T lymphocytes during toxic epidermal necrolysis are functional cytotoxic cells which express human natural killer (NK) inhibitory receptors.
MHCD0306 was used in flow cytometry to characterize the cells present in the cutaneous blister fluid patients with toxic epidermal necrolysis.
|Le Cleach L,Delaire S,Boumsell L,Bagot M,Bourgault-Villada I,Bensussan A,Roujeau JC||Clinical and experimental immunology (119:225)||2000|
Retrovirally transduced CD34++ human cord blood cells generate T cells expressing high levels of the retroviral encoded green fluorescent protein marker in vitro.
MHCD0306 was used in flow cytometry to report an in vitro assay for thymic T-cell development.
|Verhasselt B,De Smedt M,Verhelst R,Naessens E,Plum J||Blood (91:431)||1998|
CD3 antigen; CD3 antigen, delta subunit; CD3 delta; CD3-DELTA; CD3/TCR complex; CD3d; CD3d antigen; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule, delta (CD3-TCR complex); delta chain; delta polypeptide TiT3 complex; delta subunit; OKT3; OKT3, delta chain; T-cell receptor T3 delta chain; T-cell surface glycoprotein CD3 delta chain; T3D
CD3-DELTA; CD3D; IMD19; T3D