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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Armenian hamster / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids 151-164 of mouse CD3 zeta.|
|Storage buffer||TBS, pH 8|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, store in dark, DO NOT FREEZE!|
|Tested Applications||Dilution *|
|Flow Cytometry (FACS)||2 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD247 antigen; CD247 antigen, zeta subunit; CD3 antigen, zeta polypeptide; CD3-zeta/eta; CD3Z antigen, zeta polypeptide (TiT3 complex); CD3zeta chain; T-cell antigen receptor complex, zeta subunit of CD3; T-cell receptor T3 eta chain; T-cell receptor T3 zeta chain; T-cell surface glycoprotein CD3 zeta chain; TCR zeta chain
4930549J05Rik; A430104F18Rik; AW552088; Cd3; Cd3-eta; CD3-ZETA; CD3H; CD3Q; CD3Z; Cd3zeta; RP11-104L21.1; T3Z; Tcrk; TCRZ