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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||human peripheral blood T lymphocytes|
|Conjugate||FITC , PE|
|Storage buffer||PBS with 0.2% carrier protein|
|Contains||0.08% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is a monoclonal mixture of FITC-conjugated CD4 (clone 7E14, isotype IgG1) and PE-conjugated HLADR (clone 423L, isotype IgG2a).
The CD4 antigen is involved in the recognition of the type II MHC antigen. It is also a receptor for HIV. It is present on most T helper cells and normal thymocytes. The cytoplasmic portion of CD4 is associated with p56lck tyrosine kinase. CD4 expression is commonly found in human lymph nodes and tonsils. The antibody is useful for detection of HLA-DR positive B-cells, T-cells, monocytes in cell suspensions and frozen sections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD4; CD4 antigen (p55); CD4 antigen p55; CD4 receptor; CD74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule, major histocompatibility complex, class II invariant chain; DHLAG; gamma chain of class II antigens; HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; HLADG; Ia antigen-associated invariant chain; Ia-associated invariant chain; IA-gamma; Ii; MHC HLA-DR gamma chain; p33; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4
CD4; CD4mut; CD74; DHLAG; HLADG; Ia-GAMMA; II