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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Recombinant fragment of human CD40.|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||0.5-1 µg/ml|
|Western Blot (WB)||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-24740 detects CD40 from human samples. MA1-24740 will not react with mouse.
MA1-24740 has been successfully used in Western blot and ELISA procedures.
The MA1-24740 immunogen is a recombinant fragment of human CD40.
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
The CD40 antigen is a single chain glycoprotein. It is known to be a member of the tumor necrosis factor / nerve growth factor superfamily and shows a significant homology to the Hodgkin's disease associated antigen, CD30. CD40 is present on all B cells except plasma cells. It is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. The precise function of the CD40 antigen is unknown but it appears to be involved in the transduction of regulatory signals for cellular functions such as B cell proliferation and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
B cell surface antigen CD40; B cell-associated molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDW40; MGC9013; TNFRSF5
Bp50; CD40; CDW40; p50; TNFRSF5