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Mouse anti Sheep CD41/CD61 antibody, clone CO.35E4 recognizes ruminant CD41/CD61, also known as GpIIb/IIIa. CD41/CD61 is a calcium-complex dependent heterodimer and is expressed almost exclusively on platelets and on their precursors, the megakaryocytes.
CD41 is a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD61 non-covalently associates with CD41.
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Protein Aliases: glycoprotein GPIIb; glycoprotein GPIIIa; glycoprotein IIb; glycoprotein IIIa; integrin alpha 2b; Integrin alpha-2b; integrin beta 3; integrin beta 3 subunit; integrin beta3; integrin subunit alpha IIb; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B); integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGA2B-like protein; platelet glycoprotein IIb; platelet glycoprotein IIIa integrin subunit beta 3
Gene Aliases: GPIIB; GPIIIA; INTB3
Entrez Gene ID: (Bovine) 515011, (Goat) 102183451, (Sheep) 101115719, (Rabbit) 100008734, (Dog) 403789, (Horse) 100009697, (Dog) 403788, (Rabbit) 100008735, (Sheep) 100423047, (Goat) 102169417, (Bovine) 282642, (Horse) 100009709
Molecular Function: integrin
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