|Tested species reactivity||Dog, Horse, Cat, Human, Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Rat / IgG2b|
|Immunogen||Dexamethasone-induced cells of the SJL mouse spontaneous myeloid leukemia M1|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, store in dark, DO NOT FREEZE!|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||2 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Immunogenicity of undifferentiated and differentiated allogeneic mouse mesenchymal stem cells.
MA1-10229 was used in flow cytometry to study the immunogenicity and immunomodulatory properties of bone marrow-derived mesenchymal stem cells using an allogeneic mouse model.
|Mukonoweshuro B,Brown CJ,Fisher J,Ingham E||Journal of tissue engineering (5:null)||2014|