|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Glutathione S Transferase (GST) fusion protein corresponding to the variable domains (v3 to v10) of human CD44.|
|Storage buffer||TBS with 1% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||4°C or -20°C if preferred, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Neat|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 1 publications below|
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Erythropoietin-driven proliferation of cells with mutations in the tumor suppressor gene TSC2.
MA5-16966 was used in flow cytometry to assess the effects of erythropoietin in human cells with loss of tuberin function
|Ikeda Y,Taveira-DaSilva AM,Pacheco-Rodriguez G,Steagall WK,El-Chemaly S,Gochuico BR,May RM,Hathaway OM,Li S,Wang JA,Darling TN,Stylianou M,Moss J||American journal of physiology. Lung cellular and molecular physiology (300:L64)||2011|