|Tested species reactivity||Human, Non-human primate|
|Published species reactivity||Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:50-1:100 (10 µl for 10^6 cells in 100 µl)|
|Immunohistochemistry (Frozen) (IHC (F))||Assay dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50|
|Immunoprecipitation (IP)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 1 publications below|
MA1-90840 detects CD45RB from non-human primate, human samples.
MA1-90840 has been successfully used in immunohistochemistry (frozen tissue), immunohistochemistry (paraffin tissue), immunoprecipitation applications.
The MA1-90840 immunogen is: Purified MEM55
CD45RB is an alternatively spliced form of CD45, a cell surface glycoprotein. It is expressed on on peripheral B cells, T cytotoxic cells and CD4+ T cells. It has a role in cell signalling regulation through the activation of the Src family of tyrosine ki
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
CD4+ PD-1+ T cells accumulate as unique anergic cells in rheumatoid arthritis synovial fluid.
MA1-90840 was used in flow cytometry to investigate the involvement of the PD-1 system in rheumatoid arthritis
|Hatachi S,Iwai Y,Kawano S,Morinobu S,Kobayashi M,Koshiba M,Saura R,Kurosaka M,Honjo T,Kumagai S||The Journal of rheumatology (30:1410)||2003|