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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 19 amino acid peptide near the center of human SLAMF2.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-2 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control is rat lung tissue lysate.
PA5-21134 can be used with blocking peptide PEP-1248.
The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
B-lymphocyte activation marker BLAST-1; BCM1; BCM1 surface antigen; BLAST; BLAST-1; BLAST1; CD48; CD48 antigen; CD48 antigen (B-cell membrane protein); CD48d; hCD48; HM48-1; Leukocyte antigen MEM-102; mCD48; MEM-102; MRC OX-45 surface antigen; sgp-60; Signaling lymphocytic activation molecule 2; SLAM family member 2; SLAMF2; TCT.1
AI449234; AW610730; Bcm-1; BCM1; BLAST; BLAST-1; BLAST1; CD48; hCD48; mCD48; MEM-102; Sgp-60; SLAMF2