|Tested species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||C3H.CE - Ly 1.2 : DS.|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1 ug/1 million cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 3 publications below|
MA1-70072 detects CD5 in mouse samples.
MA1-70072 has been successfully used in flow cytometry procedures.
The MA1-70072 immunogen is C3H.CE - Ly 1.2 : DS.
CD5 is a 67kDa human T-lymphocyte single-chain transmembrane glycoprotein. It is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. It also reacts with a subpopulation of activated B-cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Involvement of p38 mitogen-activated protein kinase in different stages of thymocyte development.
MA1-70072 was used in flow cytometry to suggest that p38 is involved in positive selection of T cells.
|Hsu SC,Wu CC,Han J,Lai MZ||Blood (101:970)||2003|
Increased p300 expression inhibits glucocorticoid receptor-T-cell receptor antagonism but does not affect thymocyte positive selection.
MA1-70072 was used in flow cytometry to test if T-cell-specific expression of p300 alters GR-TCR cross talk between thymocytes.
|Yu CT,Feng MH,Shih HM,Lai MZ||Molecular and cellular biology (22:4556)||2002|
Targets of p56(lck) activity in immature thymoblasts: stimulation of the Ras/Raf/MAPK pathway.
MA1-70072 was used in flow cytometry to demonstrate that the Ras/Raf/MAPK pathway is constitutively activated in lck-transformed immature thymoblasts.
|Lin K,Abraham KM||International immunology (9:291)||1997|