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Applications | Tested Dilution | Publications |
---|---|---|
Flow Cytometry (Flow) |
1:25-1:100 | - |
Product Specifications | |
---|---|
Species Reactivity |
Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Recombinant Monoclonal |
Type |
Antibody |
Clone |
249 |
Immunogen |
Recombinant Mouse CD5/Cluster of Differentiation 5 Protein |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS |
Contains |
no preservative |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2866658 |
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD antigen CD5; CD5; CD5 antigen (p56 62); CD5 antigen p56-62; fCD5; Ly-1; Ly12; LyA; Lymphocyte antigen 1; Pan T cell; T-cell surface glycoprotein CD5
Gene Aliases: Cd5; Ly-1; Ly-12; Ly-A; Lyt-1
UniProt ID: (Mouse) P13379
Entrez Gene ID: (Mouse) 12507
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