|Flow Cytometry (Flow)||10 ul/10^6 cells|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG2b|
|Excitation/Emission Profile||View spectra|
|Storage buffer||PBS with 0.2% BSA|
|Contains||15mM sodium azide|
|Storage conditions||4° C, store in dark, DO NOT FREEZE!|
CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cambridge pathology 1 antigen; CAMPATH-1 antigen; CD52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CDW52; CDW52 antigen (CAMPATH-1 antigen); Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; He5; HEL-S-171mP; Human epididymis-specific protein 5
Gene Aliases: CD52; CDW52; HE5
UniProt ID: (Human) P31358
Entrez Gene ID: (Human) 1043
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.