|Flow Cytometry (Flow)||Neat-1:10|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||The details of the immunogen for this antibody are not currently available.|
|Excitation/Emission Profile||View spectra|
|Storage buffer||PBS with 1% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred, store in dark|
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
Human CD54, also known as intercellular adhesion molecule-1 (ICAM1), is a 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with CD50 (ICAM3) and with CD102 (ICAM2). ICAM1 (CD54) is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase in inflammation. Also, ICAM1 (CD54) is detected in some carcinoma and melanoma cells. Soluble ICAM1 (CD54) is detectable in the plasma and is elevated in patients with various inflammatory syndromes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD55; CD55 antigen; CD55 molecule, decay accelerating factor for complement (Cromer blood group); Complement decay-accelerating factor; CROM; DAF; RP11-357P18.1; TC
Gene Aliases: CD55; CR; CROM; DAF; TC
UniProt ID: (Human) P08174
Entrez Gene ID: (Human) 1604
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