|Tested species reactivity||Human, Non-human primate|
|Published species reactivity||Mouse|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||KG-1 human acute myelogenous leukaemia cell line.|
|Storage buffer||PBS with 0.2% BSA|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, store in dark, DO NOT FREEZE!|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||10µl/10^6 cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 1 publications below|
CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Grb10 deletion enhances muscle cell proliferation, differentiation and GLUT4 plasma membrane translocation.
MA1-19462 was used in flow cytometry to study the increased muscle cell differentiation/proliferation and plama membrane translocation of Glut4 in mice deleted for Grb10
|Mokbel N,Hoffman NJ,Girgis CM,Small L,Turner N,Daly RJ,Cooney GJ,Holt LJ||Journal of cellular physiology (229:1753)||2014|