Product References
A platinum@polymer-catechol nanobraker enables radio-immunotherapy for crippling melanoma tumorigenesis, angiogenesis, and radioresistance.
Bioactive materials
Li W,Yan J,Tian H,Li B,Wang G,Sang W,Zhang Z,Zhang X,Dai Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Microbiota-assisted iron uptake promotes immune tolerance in the intestine.
Nature communications
Zhu L,Li G,Liang Z,Qi T,Deng K,Yu J,Peng Y,Zheng J,Song Y,Chang X
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Mon May 15 00:00:00 EDT 2023
RORγt-Raftlin1 complex regulates the pathogenicity of Th17 cells and colonic inflammation.
Nature communications
Singh AK,Kumar R,Yin J,Brooks Ii JF,Kathania M,Mukherjee S,Kumar J,Conlon KP,Basrur V,Chen Z,Han X,Hooper LV,Burstein E,Venuprasad K
47-0621-82 was used in Flow cytometry/Cell sorting to identify a mechanism that drives the pathogenic function of Th17 cells, which could provide a platform for advanced therapeutic strategies to dampen Th17-mediated inflammatory diseases.
Thu Aug 17 00:00:00 EDT 2023
Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity.
Nature communications
Read KA,Jones DM,Pokhrel S,Hales EDS,Varkey A,Tuazon JA,Eisele CD,Abdouni O,Saadey A,Leonard MR,Warren RT,Powell MD,Boss JM,Hemann EA,Yount JS,Xin G,Ghoneim HE,Lio CJ,Freud AG,Collins PL,Oestreich KJ
47-0621-82 was used in Flow cytometry/Cell sorting to identify Aiolos as a pivotal regulator of CD4-CTL and TFH programming and highlight its potential as a target for manipulating CD4+ T cell responses.
Fri Mar 24 00:00:00 EDT 2023
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.
Nature communications
Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Wed Feb 16 00:00:00 EST 2022
Amphiphile-CpG vaccination induces potent lymph node activation and COVID-19 immunity in mice and non-human primates.
NPJ vaccines
Seenappa LM,Jakubowski A,Steinbuck MP,Palmer E,Haqq CM,Carter C,Fontenot J,Villinger F,McNeil LK,DeMuth PC
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Fri Oct 28 00:00:00 EDT 2022
Impact of secondary TCR engagement on the heterogeneity of pathogen-specific CD8+ T cell response during acute and chronic toxoplasmosis.
PLoS pathogens
Shallberg LA,Phan AT,Christian DA,Perry JA,Haskins BE,Beiting DP,Harris TH,Koshy AA,Hunter CA
47-0621-82 was used in flow cytometry to highlight that recent TCR activation contributes to the phenotypic heterogeneity of the CD8+ T cell response but suggest that this process has a limited impact on memory populations at acute and chronic stages of infection.
Wed Jun 01 00:00:00 EDT 2022
A unified atlas of CD8 T cell dysfunctional states in cancer and infection.
Molecular cell
Pritykin Y,van der Veeken J,Pine AR,Zhong Y,Sahin M,Mazutis L,Pe'er D,Rudensky AY,Leslie CS
47-0621-82 was used in Flow cytometry/Cell sorting to show that our atlas of CD8 T cell states will facilitate mechanistic studies of T cell immunity and translational efforts.
Thu Jun 03 00:00:00 EDT 2021
Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination.
EMBO molecular medicine
Müller K,Gibbins MP,Roberts M,Reyes-Sandoval A,Hill AVS,Draper SJ,Matuschewski K,Silvie O,Hafalla JCR
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Fri Apr 09 00:00:00 EDT 2021
Freeze-Drying Formulations Increased the Adenovirus and Poxvirus Vaccine Storage Times and Antigen Stabilities.
Virologica Sinica
Chen Y,Liao Q,Chen T,Zhang Y,Yuan W,Xu J,Zhang X
47-0621 was used in Flow cytometry/Cell sorting to develop a freeze-drying formula consisting of bovine serum albumin (BSA), L-glutamic acid (L-Glu), polyethylene glycol (PEG), and dextran (DEX) to improve the thermal stability and activity of viral vaccines, including vaccinia recombinant vaccine (rTTV-OVA) and adenovirus vaccine (Ad5-ENV).
Tue Jun 01 00:00:00 EDT 2021
Sirt6 Regulates the Development of Medullary Thymic Epithelial Cells and Contributes to the Establishment of Central Immune Tolerance.
Frontiers in cell and developmental biology
Zhang Q,Liang Z,Zhang J,Lei T,Dong X,Su H,Chen Y,Zhang Z,Tan L,Zhao Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Wed Apr 21 00:00:00 EDT 2021
Trichinella spiralis Paramyosin Induces Colonic Regulatory T Cells to Mitigate Inflammatory Bowel Disease.
Frontiers in cell and developmental biology
Hao C,Wang W,Zhan B,Wang Z,Huang J,Sun X,Zhu X
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Tue Aug 03 00:00:00 EDT 2021
CD8+ T cells in the central nervous system of mice with herpes simplex infection are highly activated and express high levels of CCR5 and CXCR3.
Journal of neurovirology
Lind L,Svensson A,Thörn K,Krzyzowska M,Eriksson K
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
cDC1 Dependent Accumulation of Memory T Cells Is Required for Chronic Autoimmune Inflammation in Murine Testis.
Frontiers in immunology
Jing Y,Cao M,Zhang B,Long X,Wang X
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Fri Sep 24 00:00:00 EDT 2021
Evaluation of DNA-Launched Virus-Like Particle Vaccines in an Immune Competent Mouse Model of Chikungunya Virus Infection.
Vaccines
Rayner JO,Kim JH,Roberts RW,Wood RR,Fouty B,Solodushko V
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Fri Apr 02 00:00:00 EDT 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression.
iScience
AbuEid M,McAllister DM,McOlash L,Harwig MC,Cheng G,Drouillard D,Boyle KA,Hardy M,Zielonka J,Johnson BD,Hill RB,Kalyanaraman B,Dwinell MB
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Fri Jun 25 00:00:00 EDT 2021
Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis.
Nature communications
Li H,Wang M,Huang B,Zhu SW,Zhou JJ,Chen DR,Cui R,Zhang M,Sun ZJ
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Thu Dec 09 00:00:00 EST 2021
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell reports
Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation.
Frontiers in immunology
Liu J,Liu Y,Panda S,Liu A,Lei J,Burd I
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
Near-infrared photoimmunotherapy targeting human-EGFR in a mouse tumor model simulating current and future clinical trials.
EBioMedicine
Okada R,Furusawa A,Vermeer DW,Inagaki F,Wakiyama H,Kato T,Nagaya T,Choyke PL,Spanos WC,Allen CT,Kobayashi H
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy.
Journal of neuroinflammation
Oladiran O,Shi XQ,Yang M,Fournier S,Zhang J
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Mon Mar 22 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis.
Nature communications
Wang G,Xie L,Li B,Sang W,Yan J,Li J,Tian H,Li W,Zhang Z,Tian Y,Dai Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2021
Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity.
Frontiers in immunology
Kalim KW,Yang JQ,Modur V,Nguyen P,Li Y,Zheng Y,Guo F
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Tue Jan 11 00:00:00 EST 2022
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry.
STAR protocols
Skordos I,Demeyer A,Beyaert R
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy.
Immunity
Milner JJ,Toma C,He Z,Kurd NS,Nguyen QP,McDonald B,Quezada L,Widjaja CE,Witherden DA,Crowl JT,Shaw LA,Yeo GW,Chang JT,Omilusik KD,Goldrath AW
47-0621 was used in Flow cytometry/Cell sorting to identify discrete lineages of intestinal antigen-specific CD8+ T cells, including a Blimp1hiId3lo tissue-resident effector cell population most prominent in the early phase of acute viral and bacterial infections and a molecularly distinct Blimp1loId3hi tissue-resident memory population that subsequently accumulated at later infection time points.
Tue May 19 00:00:00 EDT 2020
Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms.
Immunity
Beltra JC,Manne S,Abdel-Hakeem MS,Kurachi M,Giles JR,Chen Z,Casella V,Ngiow SF,Khan O,Huang YJ,Yan P,Nzingha K,Xu W,Amaravadi RK,Xu X,Karakousis GC,Mitchell TC,Schuchter LM,Huang AC,Wherry EJ
47-0621-82 was used in Flow cytometry/Cell sorting to reveal a four-stage developmental hierarchy for Tex cells and define the molecular, transcriptional, and epigenetic mechanisms that could provide opportunities to improve cancer immunotherapy.
Tue May 19 00:00:00 EDT 2020
B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer's Patches.
Cell reports
Biram A,Winter E,Denton AE,Zaretsky I,Dassa B,Bemark M,Linterman MA,Yaari G,Shulman Z
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Tue Feb 11 00:00:00 EST 2020
Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis.
Nature communications
Sidwell T,Liao Y,Garnham AL,Vasanthakumar A,Gloury R,Blume J,Teh PP,Chisanga D,Thelemann C,de Labastida Rivera F,Engwerda CR,Corcoran L,Kometani K,Kurosaki T,Smyth GK,Shi W,Kallies A
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Tue Jan 14 00:00:00 EST 2020
Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross.
Cell reports
Martin MD,Sompallae R,Winborn CS,Harty JT,Badovinac VP
47-0621 was used in Flow cytometry/Cell sorting to advance the utility of the Collaborative Cross (CC) as a tool to analyze the immune response to viral infection.
Tue Apr 14 00:00:00 EDT 2020
Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses.
Science advances
Chao Y,Liang C,Tao H,Du Y,Wu D,Dong Z,Jin Q,Chen G,Xu J,Xiao Z,Chen Q,Wang C,Chen J,Liu Z
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
Localized Treatment with Oncolytic Adenovirus Delta-24-RGDOX Induces Systemic Immunity against Disseminated Subcutaneous and Intracranial Melanomas.
Clinical cancer research : an official journal of the American Association for Cancer Research
Jiang H,Shin DH,Nguyen TT,Fueyo J,Fan X,Henry V,Carrillo CC,Yi Y,Alonso MM,Collier TL,Yuan Y,Lang FF,Gomez-Manzano C
47-0621 was used in Flow cytometry/Cell sorting to show that localized intratumoral injection of Delta-24-RGDOX induces an in situ antovaccination of the treated melanoma, the effect of which changes the immune landscape of the treated mice, resulting in systemic immunity against disseminated s.c. and i.c. tumors.
Fri Nov 15 00:00:00 EST 2019
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Nature communications
Cao Y,Trillo-Tinoco J,Sierra RA,Anadon C,Dai W,Mohamed E,Cen L,Costich TL,Magliocco A,Marchion D,Klar R,Michel S,Jaschinski F,Reich RR,Mehrotra S,Cubillos-Ruiz JR,Munn DH,Conejo-Garcia JR,Rodriguez PC
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Wed Mar 20 00:00:00 EDT 2019
Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.
Cell reports
Choi H,Deng J,Li S,Silk T,Dong L,Brea EJ,Houghton S,Redmond D,Zhong H,Boiarsky J,Akbay EA,Smith PD,Merghoub T,Wong KK,Wolchok JD
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Tue Apr 16 00:00:00 EDT 2019
Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome.
Nature communications
Komban RJ,Strömberg A,Biram A,Cervin J,Lebrero-Fernández C,Mabbott N,Yrlid U,Shulman Z,Bemark M,Lycke N
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Mon Jun 03 00:00:00 EDT 2019
MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance.
Autophagy
Liang Z,Zhang L,Su H,Luan R,Na N,Sun L,Zhao Y,Zhang X,Zhang Q,Li J,Zhang L,Zhao Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Fri Mar 22 00:00:00 EDT 2019
De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages.
Frontiers in immunology
Stüve P,Minarrieta L,Erdmann H,Arnold-Schrauf C,Swallow M,Guderian M,Krull F,Hölscher A,Ghorbani P,Behrends J,Abraham WR,Hölscher C,Sparwasser TD,Berod L
47-0621-82 was used in Flow Cytometry to reveal that acetyl-CoA carboxylase 1-dependent fatty acid synthesis is a crucial mechanism in T cells, but not dendritic cells or macrophages, to fight against mycobacterial infection.
Wed Apr 10 00:00:00 EDT 2019
C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans.
JCI insight
Verghese DA,Chun N,Paz K,Fribourg M,Woodruff TM,Flynn R,Hu Y,Xiong H,Zhang W,Yi Z,Du J,Blazar BR,Heeger PS
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Thu Dec 20 00:00:00 EST 2018
Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection.
Nature communications
Rolot M,Dougall AM,Chetty A,Javaux J,Chen T,Xiao X,Machiels B,Selkirk ME,Maizels RM,Hokke C,Denis O,Brombacher F,Vanderplasschen A,Gillet L,Horsnell WGC,Dewals BG
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Tue Oct 30 00:00:00 EDT 2018
SUMOylation of ROR-γt inhibits IL-17 expression and inflammation via HDAC2.
Nature communications
Singh AK,Khare P,Obaid A,Conlon KP,Basrur V,DePinho RA,Venuprasad K
47-0621 was used in Flow cytometry/Cell sorting to define the molecular mechanisms that govern the transcription factor activity of ROR-γt in the regulation of IL-17.
Tue Oct 30 00:00:00 EDT 2018
Stability and function of regulatory T cells expressing the transcription factor T-bet.
Nature
Levine AG,Mendoza A,Hemmers S,Moltedo B,Niec RE,Schizas M,Hoyos BE,Putintseva EV,Chaudhry A,Dikiy S,Fujisawa S,Chudakov DM,Treuting PM,Rudensky AY
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Thu Jun 15 00:00:00 EDT 2017
Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment.
Cancer cell
Turaj AH,Hussain K,Cox KL,Rose-Zerilli MJJ,Testa J,Dahal LN,Chan HTC,James S,Field VL,Carter MJ,Kim HJ,West JJ,Thomas LJ,He LZ,Keler T,Johnson PWM,Al-Shamkhani A,Thirdborough SM,Beers SA,Cragg MS,Glennie MJ,Lim SH
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Mon Dec 11 00:00:00 EST 2017
Excessive expression of miR-27 impairs Treg-mediated immunological tolerance.
The Journal of clinical investigation
Cruz LO,Hashemifar SS,Wu CJ,Cho S,Nguyen DT,Lin LL,Khan AA,Lu LF
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice.
Neurobiology of disease
MacPherson KP,Sompol P,Kannarkat GT,Chang J,Sniffen L,Wildner ME,Norris CM,Tansey MG
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
Intestinal helminth infection induces highly functional resident memory CD4+ T cells in mice.
European journal of immunology
Steinfelder S,Rausch S,Michael D,Kühl AA,Hartmann S
47-0621 was used in Flow cytometry/Cell sorting to show that nonlymphoid compartments can serve as reservoirs for Th2 memory cells, and furthermore that innate effector function of Th2 memory cells is restricted to CD4⁺ memory T cells residing in the peritoneal cavity.
Wed Feb 01 00:00:00 EST 2017
The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice.
Journal of immunology (Baltimore, Md. : 1950)
Sitrin J,Suto E,Wuster A,Eastham-Anderson J,Kim JM,Austin CD,Lee WP,Behrens TW
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Tue Aug 15 00:00:00 EDT 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
The immunosuppressive enzyme IL4I1 promotes FoxP3(+) regulatory T lymphocyte differentiation.
European journal of immunology
Cousin C,Aubatin A,Le Gouvello S,Apetoh L,Castellano F,Molinier-Frenkel V
Mon Jun 01 00:00:00 EDT 2015
Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome.
Journal of immunology (Baltimore, Md. : 1950)
Li JT,Melton AC,Su G,Hamm DE,LaFemina M,Howard J,Fang X,Bhat S,Huynh KM,O'Kane CM,Ingram RJ,Muir RR,McAuley DF,Matthay MA,Sheppard D
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
Parasite Manipulation of the Invariant Chain and the Peptide Editor H2-DM Affects Major Histocompatibility Complex Class II Antigen Presentation during Toxoplasma gondii Infection.
Infection and immunity
Leroux LP,Nishi M,El-Hage S,Fox BA,Bzik DJ,Dzierszinski FS
47-0621 was used in Flow cytometry/Cell sorting to show that Toxoplasma gondii modulates the expression of key components of the MHC-II antigen presentation pathway in professional antigen-presenting cells.
Thu Oct 01 00:00:00 EDT 2015
Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model.
BioMed research international
Olsen DS,Goar WA,Nichols BA,Bailey KT,Christensen SL,Merriam KR,Reynolds PR,Wilson E,Weber KS,Bridgewater LC
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Successive site translocating inoculation potentiates DNA/recombinant vaccinia vaccination.
Scientific reports
Ren Y,Wang N,Hu W,Zhang X,Xu J,Wan Y
47-0621 was used in Flow cytometry/Cell sorting to identify further optimisations needed to get the immunogenicity of DNA vaccines closer to the level required for human use.
Tue Dec 15 00:00:00 EST 2015
Validation of a multicolor staining to monitor phosphoSTAT5 levels in regulatory T-cell subsets.
Oncotarget
Ehx G,Hannon M,Beguin Y,Humblet-Baron S,Baron F
47-0621 was used in Flow cytometry/Cell sorting to evaluate a novel staining method with the potential to monitor the responses of various Treg subsets to IL-2 therapy.
Tue Dec 22 00:00:00 EST 2015
Intravascular staining for discrimination of vascular and tissue leukocytes.
Nature protocols
Anderson KG,Mayer-Barber K,Sung H,Beura L,James BR,Taylor JJ,Qunaj L,Griffith TS,Vezys V,Barber DL,Masopust D
47-0621 was used in Flow cytometry/Cell sorting to outline a protocol for the validation and use of intravascular staining to define innate and adaptive immune cells in mice.
Wed Jan 01 00:00:00 EST 2014
T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes.
Mucosal immunology
Chu DK,Mohammed-Ali Z,Jiménez-Saiz R,Walker TD,Goncharova S,Llop-Guevara A,Kong J,Gordon ME,Barra NG,Gillgrass AE,Van Seggelen H,Khan WI,Ashkar AA,Bramson JL,Humbles AA,Kolbeck R,Waserman S,Jordana M
47-0621 was used in Flow cytometry/Cell sorting to reveal intestinal Th2 priming is initiated by an autocrine/paracrine acting CD4(+) Th cell-intrinsic IL-4 program that is controlled by DC OX40L.
Sat Nov 01 00:00:00 EDT 2014
Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms.
F1000Research
Niebling J,E Rünker A,Schallenberg S,Kretschmer K,Kempermann G
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Fri Mar 06 00:00:00 EST 2020
STAT4 is required for IL-23 responsiveness in Th17 memory cells and NKT cells.
JAK-STAT
Glosson-Byers NL,Sehra S,Kaplan MH
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2015
Establishment of a murine graft-versus-myeloma model using allogeneic stem cell transplantation.
PloS one
Binsfeld M,Beguin Y,Belle L,Otjacques E,Hannon M,Briquet A,Heusschen R,Drion P,Zilberberg J,Bogen B,Baron F,Caers J
47-0621 was used in Flow cytometry/Cell sorting to investigate the anti-myeloma effects of allo-SCT from B10.D2 mice into MHC-matched myeloma-bearing Balb/cJ mice.
Tue Dec 15 00:00:00 EST 2015
A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models.
The Journal of clinical investigation
Dai X,James RG,Habib T,Singh S,Jackson S,Khim S,Moon RT,Liggitt D,Wolf-Yadlin A,Buckner JH,Rawlings DJ
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2013
A role for LFA-1 in delaying T-lymphocyte egress from lymph nodes.
The EMBO journal
Reichardt P,Patzak I,Jones K,Etemire E,Gunzer M,Hogg N
47-0621 was used in Flow cytometry/Cell sorting to study the role of the leukocyte function-associated antigen-1 (LFA-1) during T cell migration within and away from the lymph nodes.
Wed Mar 20 00:00:00 EDT 2013
Phenotypic CD8+ T cell diversification occurs before, during, and after the first T cell division.
Journal of immunology (Baltimore, Md. : 1950)
Lemaître F,Moreau HD,Vedele L,Bousso P
47-0621 was used in Flow cytometry/Cell sorting to study the development of heterogeneous populations from single CD8(+) T cell progenies.
Thu Aug 15 00:00:00 EDT 2013
The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology.
Immunity
Hall AO,Beiting DP,Tato C,John B,Oldenhove G,Lombana CG,Pritchard GH,Silver JS,Bouladoux N,Stumhofer JS,Harris TH,Grainger J,Wojno ED,Wagage S,Roos DS,Scott P,Turka LA,Cherry S,Reiner SL,Cua D,Belkaid Y,Elloso MM,Hunter CA
47-0621 was used in Flow cytometry/Cell sorting to study the promotion of distinct Treg cell populations by the cytokines IL-27 and IFN-y, and the role they play in limiting infection induced pathology.
Fri Sep 21 00:00:00 EDT 2012
Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment.
Cell communication and signaling : CCS
Wiechert L,Németh J,Pusterla T,Bauer C,De Ponti A,Manthey S,Marhenke S,Vogel A,Klingmüller U,Hess J,Angel P
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Sat Dec 15 00:00:00 EST 2012
A role for IL-27 in limiting T regulatory cell populations.
Journal of immunology (Baltimore, Md. : 1950)
Wojno ED,Hosken N,Stumhofer JS,O'Hara AC,Mauldin E,Fang Q,Turka LA,Levin SD,Hunter CA
47-0621 was used in Flow cytometry/Cell sorting to show that mice that overexpress IL-27 had decreased Treg frequencies and developed spontaneous inflammation.
Fri Jul 01 00:00:00 EDT 2011
Modeling Sjögren's syndrome with Id3 conditional knockout mice.
Immunology letters
Guo Z,Li H,Han M,Xu T,Wu X,Zhuang Y
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Wed Mar 30 00:00:00 EDT 2011
IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis.
Journal of immunology (Baltimore, Md. : 1950)
Unsinger J,McGlynn M,Kasten KR,Hoekzema AS,Watanabe E,Muenzer JT,McDonough JS,Tschoep J,Ferguson TA,McDunn JE,Morre M,Hildeman DA,Caldwell CC,Hotchkiss RS
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2010
Modulation of naive CD4+ T-cell responses to an airway antigen during pulmonary mycobacterial infection.
Infection and immunity
Anis MM,Fulton SA,Reba SM,Harding CV,Boom WH
Published figure using CD62L (L-Selectin) monoclonal antibody (Product # 47-0621-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2007