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Staining of BALB/c splenocytes with 0.06 µg of a rat IgG2a,K PerCP-Cy®5.5 isotype control (open histogram) or 0.06 µg of rat anti-mouse CD62L/L-selectin-PerCP-Cy®5.5 monoclonal antibody (Cat. no. A14797) (filled histogram). Total viable cells were used for analysis.
|Tested species reactivity||Mouse|
|Host / Isotype||Rat / IgG2a, kappa|
|Immunogen||C3H/eb mouse B-cell lymphoma, 38C13.|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD62 antigen-like family member L, L-selectin, LAM-1, LECAM1, leukocyte adhesion molecule 1, leukocyte-endothelial cell adhesion molecule 1, lymph node homing receptor, lymphocyte antigen 22, lymphocyte surface MEL-14 antigen, SELL, LAM1, LNHR, LSEL, LYAM1, Leu-8, Lyam-1, PLNHR, hLHRc
CD62L, Ly-m22, AI528707, Ly-22, Lnhr, L-selectin, Lyam-1, LECAM-1, Lyam1