|Tested species reactivity||Human|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Cell suspensions of human lymph node.|
|Storage buffer||PBS with 1% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C, store in dark, DO NOT FREEZE!|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Membrane permeabilization is required for flow cytometry applications. For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients.
MA1-82715 was used in flow cytometry to evaluate the relationship between tumor-associated macrophage distribution patterns and ovarian cancer histotypes
|Zhang M,He Y,Sun X,Li Q,Wang W,Zhao A,Di W||Journal of ovarian research (7:null)||2014|
Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration.
MA1-82715 was used in flow cytometry to investigate the role of exosomes in inflammation and leukotriene biosynthesis
|Esser J,Gehrmann U,D'Alexandri FL,Hidalgo-Estévez AM,Wheelock CE,Scheynius A,Gabrielsson S,Rådmark O||The Journal of allergy and clinical immunology (126:1032)||2010|
HTLV-1-associated inflammatory myopathies: low proviral load and moderate inflammation in 13 patients from West Indies and West Africa.
MA1-82715 was used in immunohistochemistry to study the histology and virology of 13 West African and West Indian patients with HTLV-1 associated inflammatory myopathy
|Desdouits M,Cassar O,Maisonobe T,Desrames A,Aouba A,Hermine O,Mikol J,Polivka M,Penisson-Besnier I,Marcorelles P,Zagnoli F,Papo T,Lacour A,Amoura Z,Haroche J,Cherin P,Teixeira A,Benveniste O,Herson S,Morin AS,Mortreux F,Wattel E,Huerre M,Cumont MC,Martin-Latil S,Butler-Browne G,Gout O,Taylor G,Gessain A,Ozden S,Ceccaldi PE||Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology (57:70)||2013|
IL-10 and IL-10 receptor overexpression in oral giant cell lesions.
MA1-82715 was used in immunohistochemistry - frozen section to determine the expression of IL-10 and its receptor in central giant cell lesions and peripheral giant cell lesions.
|Syrio NF,Faria DR,Gomez RS,Gollob KJ,Dutra WO,Souza PE||Medicina oral, patologia oral y cirugia bucal (16:e488)||2011|