|Tested species reactivity||Mouse|
|Published species reactivity||Mouse, Not Applicable|
|Host / Isotype||Armenian hamster / IgG|
|Immunogen||Murine dendritic epidermal T cell line Y245.|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
CD69 is a 55-70 kD glycoprotein that under reducing conditions dissociates in 3 components (gp 26,28,34), differentially glycosylated forms of a 21kD protein. CD69 is an early activation antigen also called Activation Inducer Molecule (AIM) that is very early, before antigens such as CD25 and CD71 are expressed strongly on T-cells after activation. CD69 is also expressed by activated B-lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced disease.
A16342 was used in flow cytometry to use the Friend retrovirus mouse model to elucidate the mode of action of poly(I:C) in antiretroviral immunotherapy
|Gibbert K,Dietze KK,Zelinskyy G,Lang KS,Barchet W,Kirschning CJ,Dittmer U||Journal of immunology (Baltimore, Md. : 1950) (185:6179)||2010|
Immune enhancement of skin carcinogenesis by CD4+ T cells.
A16342 was used in flow cytometry to study the effects of bacterial infection on the CD4 T cell responses and tumorigenesis.
|Daniel D,Meyer-Morse N,Bergsland EK,Dehne K,Coussens LM,Hanahan D||The Journal of experimental medicine (197:1017)||2003|
|Not Applicable||Not Cited||
Influenza A virus elevates active cathepsin B in primary murine DC.
A16342 was used in flow cytometry to suggest that the influenza A virus affects the MHC class II antigen-processing pathway
|Burster T,Giffon T,Dahl ME,Björck P,Bogyo M,Weber E,Mahmood K,Lewis DB,Mellins ED||International immunology (19:645)||2007|