Product References
HSF1 promotes CD69+ Treg differentiation to inhibit colitis progression.
Theranostics
Yu L,Zhou B,Zhu Y,Li L,Zhong Y,Zhu L,Wang H,Chen H,Xu J,Guo T,Feng L,Wang X,Cai Z,Wang J,Jin H
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Tue Apr 18 00:00:00 EDT 2023
Novel Bruton's tyrosine kinase inhibitor TAS5315 suppresses the progression of inflammation and joint destruction in rodent collagen-induced arthritis.
PloS one
Akasaka D,Iguchi S,Kaneko R,Yoshiga Y,Kajiwara D,Nakachi Y,Noma N,Tanaka K,Shimizu A,Hosoi F
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Mon Feb 27 00:00:00 EST 2023
Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model.
Frontiers in immunology
Jiang W,Wang X,Su Y,Cai L,Li J,Liang J,Gu Q,Sun M,Shi L
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Tue May 03 00:00:00 EDT 2022
Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain.
eLife
Kovacs MA,Cowan MN,Babcock IW,Sibley LA,Still K,Batista SJ,Labuzan SA,Sethi I,Harris TH
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2022
An autonomous TCR signal-sensing switch influences CD4/CD8 lineage choice in mice.
Communications biology
Basu J,Zha J,Nicolas E,Coulton M,Czyzewicz P,Hua X,Ge L,Kappes DJ
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Fri Jan 21 00:00:00 EST 2022
An autonomous TCR signal-sensing switch influences CD4/CD8 lineage choice in mice.
Communications biology
Basu J,Zha J,Nicolas E,Coulton M,Czyzewicz P,Hua X,Ge L,Kappes DJ
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Fri Jan 21 00:00:00 EST 2022
CP-25 exerts a protective effect against ConA-induced hepatitis via regulating inflammation and immune response.
Frontiers in pharmacology
Li N,Wu JJ,Qi M,Wang ZY,Zhang SN,Li XQ,Chen TT,Wang MF,Zhang LL,Wei W,Sun WY
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Sat Dec 03 00:00:00 EST 2022
A novel costimulatory molecule gene-modified leukemia cell-derived exosome-targeted CD4+ T cell vaccine efficiently enhances anti-leukemia immunity.
Frontiers in immunology
Li J,Huang F,Jiang Y,Zhao J,Wan J,Hao S
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Tue Dec 06 00:00:00 EST 2022
Do more with Less: Improving High Parameter Cytometry Through Overnight Staining.
Current protocols
Whyte CE,Tumes DJ,Liston A,Burton OT
25-0691-82 was used in Flow cytometry/Cell sorting to demonstrate how increasing antibody incubation times can lead to substantial improvements in sensitivity, maintaining specificity, and reducing background, while also significantly reducing the costs of high-parameter cytometry panels.
Tue Nov 01 00:00:00 EDT 2022
ADAM12 is a costimulatory molecule that determines Th1 cell fate and mediates tissue inflammation.
Cellular & molecular immunology
Liu Y,Bockermann R,Hadi M,Safari I,Carrion B,Kveiborg M,Issazadeh-Navikas S
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells.
The Journal of experimental medicine
Sasai M,Ma JS,Okamoto M,Nishino K,Nagaoka H,Takashima E,Pradipta A,Lee Y,Kosako H,Suh PG,Yamamoto M
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition).
European journal of immunology
Cossarizza A,Chang HD,Radbruch A,Abrignani S,Addo R,Akdis M,Andrä I,Andreata F,Annunziato F,Arranz E,Bacher P,Bari S,Barnaba V,Barros-Martins J,Baumjohann D,Beccaria CG,Bernardo D,Boardman DA,Borger J,Böttcher C,Brockmann L,Burns M,Busch DH,Cameron G,Cammarata I,Cassotta A,Chang Y,Chirdo FG,Christakou E,Čičin-Šain L,Cook L,Corbett AJ,Cornelis R,Cosmi L,Davey MS,De Biasi S,De Simone G,Del Zotto G,Delacher M,Di Rosa F,Di Santo J,Diefenbach A,Dong J,Dörner T,Dress RJ,Dutertre CA,Eckle SBG,Eede P,Evrard M,Falk CS,Feuerer M,Fillatreau S,Fiz-Lopez A,Follo M,Foulds GA,Fröbel J,Gagliani N,Galletti G,Gangaev A,Garbi N,Garrote JA,Geginat J,Gherardin NA,Gibellini L,Ginhoux F,Godfrey DI,Gruarin P,Haftmann C,Hansmann L,Harpur CM,Hayday AC,Heine G,Hernández DC,Herrmann M,Hoelsken O,Huang Q,Huber S,Huber JE,Huehn J,Hundemer M,Hwang WYK,Iannacone M,Ivison SM,Jäck HM,Jani PK,Keller B,Kessler N,Ketelaars S,Knop L,Knopf J,Koay HF,Kobow K,Kriegsmann K,Kristyanto H,Krueger A,Kuehne JF,Kunze-Schumacher H,Kvistborg P,Kwok I,Latorre D,Lenz D,Levings MK,Lino AC,Liotta F,Long HM,Lugli E,MacDonald KN,Maggi L,Maini MK,Mair F,Manta C,Manz RA,Mashreghi MF,Mazzoni A,McCluskey J,Mei HE,Melchers F,Melzer S,Mielenz D,Monin L,Moretta L,Multhoff G,Muñoz LE,Muñoz-Ruiz M,Muscate F,Natalini A,Neumann K,Ng LG,Niedobitek A,Niemz J,Almeida LN,Notarbartolo S,Ostendorf L,Pallett LJ,Patel AA,Percin GI,Peruzzi G,Pinti M,Pockley AG,Pracht K,Prinz I,Pujol-Autonell I,Pulvirenti N,Quatrini L,Quinn KM,Radbruch H,Rhys H,Rodrigo MB,Romagnani C,Saggau C,Sakaguchi S,Sallusto F,Sanderink L,Sandrock I,Schauer C,Scheffold A,Scherer HU,Schiemann M,Schildberg FA,Schober K,Schoen J,Schuh W,Schüler T,Schulz AR,Schulz S,Schulze J,Simonetti S,Singh J,Sitnik KM,Stark R,Starossom S,Stehle C,Szelinski F,Tan L,Tarnok A,Tornack J,Tree TIM,van Beek JJP,van de Veen W,van Gisbergen K,Vasco C,Verheyden NA,von Borstel A,Ward-Hartstonge KA,Warnatz K,Waskow C,Wiedemann A,Wilharm A,Wing J,Wirz O,Wittner J,Yang JHM,Yang J
25-0691-82 was used in Flow cytometry/Cell sorting to provide the key aspects to consider when performing flow cytometry experiments.
Wed Dec 01 00:00:00 EST 2021
Fasudil prevents liver fibrosis via activating natural killer cells and suppressing hepatic stellate cells.
World journal of gastroenterology
Han QJ,Mu YL,Zhao HJ,Zhao RR,Guo QJ,Su YH,Zhang J
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
TRPM8 channel augments T-cell activation and proliferation.
Cell biology international
Acharya TK,Tiwari A,Majhi RK,Goswami C
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Cell-permeable transgelin-2 as a potent therapeutic for dendritic cell-based cancer immunotherapy.
Journal of hematology & oncology
Kim HR,Park JS,Park JH,Yasmin F,Kim CH,Oh SK,Chung IJ,Jun CD
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Wed Mar 17 00:00:00 EDT 2021
Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage.
NPJ vaccines
Dubois V,Chatagnon J,Thiriard A,Bauderlique-Le Roy H,Debrie AS,Coutte L,Locht C
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Fri Jan 08 00:00:00 EST 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure.
Cell death & disease
Yu H,Yang W,Huang J,Miao X,Wang B,Ren X,Gu Y,Wang Q,Ding X,Guo X,Qian F,Zhang Y,Xu H,Zheng L,Jin M
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Thu Dec 16 00:00:00 EST 2021
A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge.
Cell reports
Jiang W,Shi L,Cai L,Wang X,Li J,Li H,Liang J,Gu Q,Ji G,Li J,Liu L,Sun M
25-0691-82 was used in Flow cytometry/Cell sorting to suggest that the developed vaccine can elicit a multifaceted immune response and induce robust viral clearance in the URT, which makes it a potential vaccine for preventing disease and infection of SARS-CoV-2.
Tue Dec 14 00:00:00 EST 2021
Robust induction of TRMs by combinatorial nanoshells confers cross-strain sterilizing immunity against lethal influenza viruses.
Molecular therapy. Methods & clinical development
Lin PH,Liang CY,Yao BY,Chen HW,Pan CF,Wu LL,Lin YH,Hsu YS,Liu YH,Chen PJ,Hu CJ,Yang HC
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Fri Jun 11 00:00:00 EDT 2021
SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis.
iScience
Sangaletti S,Botti L,Gulino A,Lecis D,Bassani B,Portararo P,Milani M,Cancila V,De Cecco L,Dugo M,Tripodo C,Colombo MP
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Fri Jun 25 00:00:00 EDT 2021
T cell self-reactivity during thymic development dictates the timing of positive selection.
eLife
Lutes LK,Steier Z,McIntyre LL,Pandey S,Kaminski J,Hoover AR,Ariotti S,Streets A,Yosef N,Robey EA
25-0691-82 was used in Flow Cytometry to imply that thymocytes with low self-reactivity downregulate TCR sensitivity more slowly during positive selection, and associate membrane ion channel expression with thymocyte self-reactivity and progress through positive selection.
Thu Apr 22 00:00:00 EDT 2021
Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection.
Cell
Ho JSY,Angel M,Ma Y,Sloan E,Wang G,Martinez-Romero C,Alenquer M,Roudko V,Chung L,Zheng S,Chang M,Fstkchyan Y,Clohisey S,Dinan AM,Gibbs J,Gifford R,Shen R,Gu Q,Irigoyen N,Campisi L,Huang C,Zhao N,Jones JD,van Knippenberg I,Zhu Z,Moshkina N,Meyer L,Noel J,Peralta Z,Rezelj V,Kaake R,Rosenberg B,Wang B,Wei J,Paessler S,Wise HM,Johnson J,Vannini A,Amorim MJ,Baillie JK,Miraldi ER,Benner C,Brierley I,Digard P,Łuksza M,Firth AE,Krogan N,Greenbaum BD,MacLeod MK,van Bakel H,Garcìa-Sastre A,Yewdell JW,Hutchinson E,Marazzi I
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Thu Jun 25 00:00:00 EDT 2020
Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA.
Immunity
Soni C,Perez OA,Voss WN,Pucella JN,Serpas L,Mehl J,Ching KL,Goike J,Georgiou G,Ippolito GC,Sisirak V,Reizis B
25-0691-82 was used in Flow Cytometry to establish extrafollicular B cell differentiation into short-lived AFCs as a key mechanism of anti-DNA autoreactivity and reveal a major contribution of pDCs, endosomal Toll-like receptors (TLRs), and IFN-I to this pathway.
Tue Jun 16 00:00:00 EDT 2020
Contact-dependent delivery of IL-2 by dendritic cells to CD4 T cells in the contraction phase promotes their long-term survival.
Protein & cell
Tong D,Zhang L,Ning F,Xu Y,Hu X,Shi Y
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Increase in liver γδ T cells with concurrent augmentation of IFN-β production during the early stages of a mouse model of acute experimental hepatitis B virus infection.
Experimental and therapeutic medicine
Chang L,Wang L,Ling N,Peng H,Chen M
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
Effects of CD4+ T lymphocytes from ovariectomized mice on bone marrow mesenchymal stem cell proliferation and osteogenic differentiation.
Experimental and therapeutic medicine
Shao BY,Wang L,Yu Y,Chen L,Gan N,Huang WM
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Regulation of T cell receptor signaling by protein acyltransferase DHHC21.
Molecular biology reports
Fan Y,Shayahati B,Tewari R,Boehning D,Akimzhanov AM
25-0691-82 was used in Flow Cytometry to investigate if DHHC protein acyltransferases can play an essential role in regulation of T cell-mediated immunity.
Sat Aug 01 00:00:00 EDT 2020
Potentiating the Antitumor Activity of Cytotoxic T Cells via the Transmembrane Domain of IGSF4 That Increases TCR Avidity.
Frontiers in immunology
Kim HR,Park JS,Fatima Y,Kausar M,Park JH,Jun CD
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Tue Jul 27 00:00:00 EDT 2021
Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy.
Cell communication and signaling : CCS
Klepsch V,Pommermayr M,Humer D,Brigo N,Hermann-Kleiter N,Baier G
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Tue Jan 14 00:00:00 EST 2020
SLAMF6 deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint.
eLife
Hajaj E,Eisenberg G,Klein S,Frankenburg S,Merims S,Ben David I,Eisenhaure T,Henrickson SE,Villani AC,Hacohen N,Abudi N,Abramovich R,Cohen JE,Peretz T,Veillette A,Lotem M
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Tue Mar 03 00:00:00 EST 2020
Loss of testosterone impairs anti-tumor neutrophil function.
Nature communications
Markman JL,Porritt RA,Wakita D,Lane ME,Martinon D,Noval Rivas M,Luu M,Posadas EM,Crother TR,Arditi M
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Tue Mar 31 00:00:00 EDT 2020
CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis.
Journal of neuroinflammation
Funk KE,Klein RS
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Thu Jan 31 00:00:00 EST 2019
Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules.
NPJ vaccines
Andersen TK,Huszthy PC,Gopalakrishnan RP,Jacobsen JT,Fauskanger M,Tveita AA,Grødeland G,Bogen B
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Thu Oct 05 00:00:00 EDT 2023
Tumor-intrinsic response to IFNγ shapes the tumor microenvironment and anti-PD-1 response in NSCLC.
Life science alliance
Bullock BL,Kimball AK,Poczobutt JM,Neuwelt AJ,Li HY,Johnson AM,Kwak JW,Kleczko EK,Kaspar RE,Wagner EK,Hopp K,Schenk EL,Weiser-Evans MC,Clambey ET,Nemenoff RA
25-0691-82 was used in Flow Cytometry to demonstrate that targeted enhancement of tumor-intrinsic IFNγ signaling can induce a cascade of changes associated with increased therapeutic vulnerability.
Sat Jun 01 00:00:00 EDT 2019
Evaluation of antiviral - passive - active immunization ("sandwich") therapeutic strategy for functional cure of chronic hepatitis B in mice.
EBioMedicine
Shi B,Wu Y,Wang C,Li X,Yu F,Wang B,Yang Z,Li J,Liang M,Wen Y,Ying T,Yuan Z
25-0691 was used in Flow cytometry to show "sandwich" combination therapy consisting of antiviral, passive and active immunization may be effective for chronic hepatitis B as it efficiently decreases HBsAg and HBV DNA levels and induces cellular and humoral immunity.
Fri Nov 01 00:00:00 EDT 2019
A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments.
Nature medicine
Barry KC,Hsu J,Broz ML,Cueto FJ,Binnewies M,Combes AJ,Nelson AE,Loo K,Kumar R,Rosenblum MD,Alvarado MD,Wolf DM,Bogunovic D,Bhardwaj N,Daud AI,Ha PK,Ryan WR,Pollack JL,Samad B,Asthana S,Chan V,Krummel MF
25-0691 was used in Flow cytometry/Cell sorting to reveal that innate immune stimulatory dendritic cells and natural killer cells cluster together as an excellent prognostic tool for T cell-directed immunotherapy and that these innate cells are necessary for enhanced T cell tumor responses, suggesting this axis as a target for new therapies.
Wed Aug 01 00:00:00 EDT 2018
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8+ T cells.
Nature cell biology
Ma R,Ji T,Zhang H,Dong W,Chen X,Xu P,Chen D,Liang X,Yin X,Liu Y,Ma J,Tang K,Zhang Y,Peng Y,Lu J,Zhang Y,Qin X,Cao X,Wan Y,Huang B
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
Complement Activation via a C3a Receptor Pathway Alters CD4+ T Lymphocytes and Mediates Lung Cancer Progression.
Cancer research
Kwak JW,Laskowski J,Li HY,McSharry MV,Sippel TR,Bullock BL,Johnson AM,Poczobutt JM,Neuwelt AJ,Malkoski SP,Weiser-Evans MC,Lambris JD,Clambey ET,Thurman JM,Nemenoff RA
25-0691 was used in Flow cytometry/Cell sorting to study the mechanism relating complement activation to tumour progression in multiple immunocompetent orthotopic models of lung cancer.
Mon Jan 01 00:00:00 EST 2018
Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8+ T cell responses.
Journal of controlled release : official journal of the Controlled Release Society
Si Y,Wen Y,Kelly SH,Chong AS,Collier JH
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Sat Jul 28 00:00:00 EDT 2018
MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway.
Clinical and experimental immunology
Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Wed Mar 28 00:00:00 EDT 2018
MAIT cells contribute to protection against lethal influenza infection in vivo.
Nature communications
van Wilgenburg B,Loh L,Chen Z,Pediongco TJ,Wang H,Shi M,Zhao Z,Koutsakos M,Nüssing S,Sant S,Wang Z,D'Souza C,Jia X,Almeida CF,Kostenko L,Eckle SBG,Meehan BS,Kallies A,Godfrey DI,Reading PC,Corbett AJ,McCluskey J,Klenerman P,Kedzierska K,Hinks TSC
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Fri Nov 09 00:00:00 EST 2018
Homoharringtonine induced immune alteration for an Efficient Anti-tumor Response in Mouse Models of Non-small Cell Lung Adenocarcinoma Expressing Kras Mutation.
Scientific reports
Weng TY,Wu HF,Li CY,Hung YH,Chang YW,Chen YL,Hsu HP,Chen YH,Wang CY,Chang JY,Lai MD
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Tue May 29 00:00:00 EDT 2018
Development of a screening strategy for new modulators of T cell receptor signaling and T cell activation.
Scientific reports
Chen EW,Brzostek J,Gascoigne NRJ,Rybakin V
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Tue Jul 03 00:00:00 EDT 2018
Differentiation and Protective Capacity of Virus-Specific CD8+ T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche.
Immunity
Tomov VT,Palko O,Lau CW,Pattekar A,Sun Y,Tacheva R,Bengsch B,Manne S,Cosma GL,Eisenlohr LC,Nice TJ,Virgin HW,Wherry EJ
25-0691 was used in Flow cytometry/Cell sorting to elucidate a strategy of immune evasion by mouse norovirus via the induction of a CD8+ T cell program normally reserved for latent pathogens and persistence in an immune-privileged enteric niche.
Tue Oct 17 00:00:00 EDT 2017
Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance.
Nature immunology
Minguet S,Kläsener K,Schaffer AM,Fiala GJ,Osteso-Ibánez T,Raute K,Navarro-Lérida I,Hartl FA,Seidl M,Reth M,Del Pozo MA
25-0691 was used in Flow cytometry/Cell sorting to study the role of Caveolin-1 in controlling the distribution of nanoclusters of isotype-specific B cell antigen receptors on the surface of B cells.
Sun Oct 01 00:00:00 EDT 2017
Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling.
The Journal of clinical investigation
Ying W,Wollam J,Ofrecio JM,Bandyopadhyay G,El Ouarrat D,Lee YS,Oh DY,Li P,Osborn O,Olefsky JM
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo.
The Journal of experimental medicine
Lehmann CHK,Baranska A,Heidkamp GF,Heger L,Neubert K,Lühr JJ,Hoffmann A,Reimer KC,Brückner C,Beck S,Seeling M,Kießling M,Soulat D,Krug AB,Ravetch JV,Leusen JHW,Nimmerjahn F,Dudziak D
25-0691 was used in Flow cytometry/Cell sorting to suggest that targeting antigens to FcγRs on DCs may be a promising approach to raise immunogenic or tolerogenic T cell responses to antigens of choice.
Mon May 01 00:00:00 EDT 2017
IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and Fibrosis.
Journal of the American Society of Nephrology : JASN
Chi HH,Hua KF,Lin YC,Chu CL,Hsieh CY,Hsu YJ,Ka SM,Tsai YL,Liu FC,Chen A
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2017
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Intestinal helminth infection induces highly functional resident memory CD4+ T cells in mice.
European journal of immunology
Steinfelder S,Rausch S,Michael D,Kühl AA,Hartmann S
25-0691 was used in Flow cytometry/Cell sorting to show that nonlymphoid compartments can serve as reservoirs for Th2 memory cells, and furthermore that innate effector function of Th2 memory cells is restricted to CD4⁺ memory T cells residing in the peritoneal cavity.
Wed Feb 01 00:00:00 EST 2017
14-3-3 Proteins regulate K2P 5.1 surface expression on T lymphocytes.
Traffic (Copenhagen, Denmark)
Fernández-Orth J,Ehling P,Ruck T,Pankratz S,Hofmann MS,Landgraf P,Dieterich DC,Smalla KH,Kähne T,Seebohm G,Budde T,Wiendl H,Bittner S,Meuth SG
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Reactive Oxygen Species Regulate the Inflammatory Function of NKT Cells through Promyelocytic Leukemia Zinc Finger.
Journal of immunology (Baltimore, Md. : 1950)
Kim YH,Kumar A,Chang CH,Pyaram K
25-0691 was used in Flow cytometry/Cell sorting to investigate the role of reactive oxygen species in natural killer T cell function.
Wed Nov 15 00:00:00 EST 2017
IRF6 Regulates Alternative Activation by Suppressing PPARγ in Male Murine Macrophages.
Endocrinology
Li C,Ying W,Huang Z,Brehm T,Morin A,Vella AT,Zhou B
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.
Nature communications
Wang Q,Ning H,Peng H,Wei L,Hou R,Hoft DF,Liu J
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2017
IL-27R signaling controls myeloid cells accumulation and antigen-presentation in atherosclerosis.
Scientific reports
Peshkova IO,Fatkhullina AR,Mikulski Z,Ley K,Koltsova EK
25-0691 was used in Flow cytometry/Cell sorting to study the role of IL-27R in controlling myeloid cell accumulation and activation in atherosclerosis.
Tue May 23 00:00:00 EDT 2017
NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20.
The Journal of experimental medicine
Drennan MB,Govindarajan S,Verheugen E,Coquet JM,Staal J,McGuire C,Taghon T,Leclercq G,Beyaert R,van Loo G,Lambrecht BN,Elewaut D
25-0691 was used in Flow cytometry/Cell sorting to show that negative regulation of TCR signalling during NKT development controls the differentiation and survival of NKT1 and NKT2 cells.
Mon Sep 19 00:00:00 EDT 2016
Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress.
The Journal of experimental medicine
Zamora-Pineda J,Kumar A,Suh JH,Zhang M,Saba JD
25-0691 was used in Flow cytometry/Cell sorting to investigate the role of dendritic cell sphingosine-1-phosphate lyase in thymic egress.
Mon Nov 14 00:00:00 EST 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells.
eLife
Allison KA,Sajti E,Collier JG,Gosselin D,Troutman TD,Stone EL,Hedrick SM,Glass CK
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Mon Jul 04 00:00:00 EDT 2016
MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.
The Journal of clinical investigation
Ying W,Tseng A,Chang RC,Morin A,Brehm T,Triff K,Nair V,Zhuang G,Song H,Kanameni S,Wang H,Golding MC,Bazer FW,Chapkin RS,Safe S,Zhou B
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Mon Nov 02 00:00:00 EST 2015
Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells.
Frontiers in immunology
Vogel AJ,Brown DM
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Fri Jul 10 00:00:00 EDT 2015
MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation.
Stem cell reports
Tan Y,AlKhamees B,Jia D,Li L,Couture JF,Figeys D,Jinushi M,Wang L
25-0691 was used in Flow cytometry/Cell sorting to elucidate the molecules and mechanisms pertinent to the low immunogenicity of undifferentiated embryonic stem cells.
Tue Nov 10 00:00:00 EST 2015
Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.
Oncoimmunology
Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
Natural killer cell NKG2D and granzyme B are critical for allergic pulmonary inflammation.
The Journal of allergy and clinical immunology
Farhadi N,Lambert L,Triulzi C,Openshaw PJ,Guerra N,Culley FJ
25-0691 was used in Flow cytometry/Cell sorting to investigate the importance of natural killer cells in house dust mite-triggered allergic response.
Sat Mar 01 00:00:00 EST 2014
mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function.
Journal of immunology (Baltimore, Md. : 1950)
Donnelly RP,Loftus RM,Keating SE,Liou KT,Biron CA,Gardiner CM,Finlay DK
25-0691 was used in Flow cytometry/Cell sorting to investigate whether mTORC1-controlled metabolism underpins normal natural killer cell proinflammatory functions.
Sat Nov 01 00:00:00 EDT 2014
Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock.
PloS one
Hou H,Liu W,Wu S,Lu Y,Peng J,Zhu Y,Lu Y,Wang F,Sun Z
Published figure using CD69 monoclonal antibody (Product # 25-0691-82) in Flow Cytometry
Mon Jul 06 00:00:00 EDT 2015
Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation.
Nature communications
Fu H,Kishore M,Gittens B,Wang G,Coe D,Komarowska I,Infante E,Ridley AJ,Cooper D,Perretti M,Marelli-Berg FM
25-0691 was used in Flow cytometry/Cell sorting to explain the mechanisms underlying the powerful migratory capacity of Treg cells and their ability to maintain optimal T cell ratios.
Fri Mar 14 00:00:00 EDT 2014
Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy.
Nature communications
Burton BR,Britton GJ,Fang H,Verhagen J,Smithers B,Sabatos-Peyton CA,Carney LJ,Gough J,Strobel S,Wraith DC
25-0691 was used in Flow cytometry/Cell sorting to study the markers significant for antigen-specific immunotherapy such as regulatory CD4(+) T-cell transcription factors.
Wed Sep 03 00:00:00 EDT 2014
Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology
Macritchie N,Grassia G,Sabir SR,Maddaluno M,Welsh P,Sattar N,Ialenti A,Kurowska-Stolarska M,McInnes IB,Brewer JM,Garside P,Maffia P
25-0691 was used in Flow cytometry/Cell sorting to identify a potential role for pDC targeting in the control of the pathology of coronary artery disease.
Thu Nov 01 00:00:00 EDT 2012
Fates of CD4+ T cells in a tolerant environment depend on timing and place of antigen exposure.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Burrell BE,Bromberg JS
25-0691 was used in Flow cytometry/Cell sorting to elucidate the key factors that determine the fate of graft reactive T cells.
Thu Mar 01 00:00:00 EST 2012
Nitric oxide inhibits the accumulation of CD4+CD44hiTbet+CD69lo T cells in mycobacterial infection.
European journal of immunology
Pearl JE,Torrado E,Tighe M,Fountain JJ,Solache A,Strutt T,Swain S,Appelberg R,Cooper AM
25-0691 was used in Flow cytometry/Cell sorting to support the hypothesis that effector T cells in mycobacterial granulomata are not a uniform effector population but exist in distinct subsets with differential susceptibility to the regulatory effects of nitric oxide.
Sat Dec 01 00:00:00 EST 2012
Selective reduction of post-selection CD8 thymocyte proliferation in IL-15Rα deficient mice.
PloS one
Chow KP,Qiu JT,Lee JM,Hsu SL,Yang SC,Wu NN,Huang W,Wu TS
25-0691 was used in Flow cytometry/Cell sorting to investigate the unique IL-15-dependent cell expansion at the mature CD8SP stage of thymocyte development.
Mon Aug 20 00:00:00 EDT 2012
Debridement increases survival in a mouse model of subcutaneous anthrax.
PloS one
Weiner ZP,Boyer AE,Gallegos-Candela M,Cardani AN,Barr JR,Glomski IJ
25-0691 was used in Flow cytometry/Cell sorting to develop a mouse model of debridement to evaluate its effectiveness in the treatment of Bacillus anthracis soft tissue infections.
Mon Jul 23 00:00:00 EDT 2012
Interplay between CD8α+ dendritic cells and monocytes in response to Listeria monocytogenes infection attenuates T cell responses.
PloS one
Kapadia D,Sadikovic A,Vanloubbeeck Y,Brockstedt D,Fong L
25-0691 was used in Flow cytometry/Cell sorting to examine the contribution of different primary APCs during Listeria monocytogenes infection, showing interplay between dendritic cells and monocytes during infection.
Fri Apr 29 00:00:00 EDT 2011
Modulation of naive CD4+ T-cell responses to an airway antigen during pulmonary mycobacterial infection.
Infection and immunity
Anis MM,Fulton SA,Reba SM,Harding CV,Boom WH
25-0691 was used in Flow cytometry/Cell sorting to demonstrate that infection alters lung DCs for activation of antigen-specific lung T cells in response to airway antigen challenge.
Tue May 01 00:00:00 EDT 2007