Product References
HSF1 promotes CD69+ Treg differentiation to inhibit colitis progression.
Theranostics
Yu L,Zhou B,Zhu Y,Li L,Zhong Y,Zhu L,Wang H,Chen H,Xu J,Guo T,Feng L,Wang X,Cai Z,Wang J,Jin H
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Tue Apr 18 00:00:00 EDT 2023
Novel Bruton's tyrosine kinase inhibitor TAS5315 suppresses the progression of inflammation and joint destruction in rodent collagen-induced arthritis.
PloS one
Akasaka D,Iguchi S,Kaneko R,Yoshiga Y,Kajiwara D,Nakachi Y,Noma N,Tanaka K,Shimizu A,Hosoi F
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Mon Feb 27 00:00:00 EST 2023
Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model.
Frontiers in immunology
Jiang W,Wang X,Su Y,Cai L,Li J,Liang J,Gu Q,Sun M,Shi L
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Tue May 03 00:00:00 EDT 2022
Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain.
eLife
Kovacs MA,Cowan MN,Babcock IW,Sibley LA,Still K,Batista SJ,Labuzan SA,Sethi I,Harris TH
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2022
An autonomous TCR signal-sensing switch influences CD4/CD8 lineage choice in mice.
Communications biology
Basu J,Zha J,Nicolas E,Coulton M,Czyzewicz P,Hua X,Ge L,Kappes DJ
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Fri Jan 21 00:00:00 EST 2022
CP-25 exerts a protective effect against ConA-induced hepatitis via regulating inflammation and immune response.
Frontiers in pharmacology
Li N,Wu JJ,Qi M,Wang ZY,Zhang SN,Li XQ,Chen TT,Wang MF,Zhang LL,Wei W,Sun WY
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Sat Dec 03 00:00:00 EST 2022
A novel costimulatory molecule gene-modified leukemia cell-derived exosome-targeted CD4+ T cell vaccine efficiently enhances anti-leukemia immunity.
Frontiers in immunology
Li J,Huang F,Jiang Y,Zhao J,Wan J,Hao S
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Tue Dec 06 00:00:00 EST 2022
ADAM12 is a costimulatory molecule that determines Th1 cell fate and mediates tissue inflammation.
Cellular & molecular immunology
Liu Y,Bockermann R,Hadi M,Safari I,Carrion B,Kveiborg M,Issazadeh-Navikas S
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells.
The Journal of experimental medicine
Sasai M,Ma JS,Okamoto M,Nishino K,Nagaoka H,Takashima E,Pradipta A,Lee Y,Kosako H,Suh PG,Yamamoto M
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Fasudil prevents liver fibrosis via activating natural killer cells and suppressing hepatic stellate cells.
World journal of gastroenterology
Han QJ,Mu YL,Zhao HJ,Zhao RR,Guo QJ,Su YH,Zhang J
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
TRPM8 channel augments T-cell activation and proliferation.
Cell biology international
Acharya TK,Tiwari A,Majhi RK,Goswami C
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Cell-permeable transgelin-2 as a potent therapeutic for dendritic cell-based cancer immunotherapy.
Journal of hematology & oncology
Kim HR,Park JS,Park JH,Yasmin F,Kim CH,Oh SK,Chung IJ,Jun CD
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Wed Mar 17 00:00:00 EDT 2021
Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage.
NPJ vaccines
Dubois V,Chatagnon J,Thiriard A,Bauderlique-Le Roy H,Debrie AS,Coutte L,Locht C
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Fri Jan 08 00:00:00 EST 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure.
Cell death & disease
Yu H,Yang W,Huang J,Miao X,Wang B,Ren X,Gu Y,Wang Q,Ding X,Guo X,Qian F,Zhang Y,Xu H,Zheng L,Jin M
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Thu Dec 16 00:00:00 EST 2021
Robust induction of TRMs by combinatorial nanoshells confers cross-strain sterilizing immunity against lethal influenza viruses.
Molecular therapy. Methods & clinical development
Lin PH,Liang CY,Yao BY,Chen HW,Pan CF,Wu LL,Lin YH,Hsu YS,Liu YH,Chen PJ,Hu CJ,Yang HC
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Fri Jun 11 00:00:00 EDT 2021
SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis.
iScience
Sangaletti S,Botti L,Gulino A,Lecis D,Bassani B,Portararo P,Milani M,Cancila V,De Cecco L,Dugo M,Tripodo C,Colombo MP
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Fri Jun 25 00:00:00 EDT 2021
ILC3s control airway inflammation by limiting T cell responses to allergens and microbes.
Cell reports
Teng F,Tachó-Piñot R,Sung B,Farber DL,Worgall S,Hammad H,Lambrecht BN,Hepworth MR,Sonnenberg GF
45-0691-82 was used in Flow cytometry/Cell sorting to demonstrate a critical role for antigen-presenting ILC3s in orchestrating immune tolerance in the airway by restricting pro-inflammatory T cell responses to both allergens and microbes.
Tue Nov 23 00:00:00 EST 2021
Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection.
Cell
Ho JSY,Angel M,Ma Y,Sloan E,Wang G,Martinez-Romero C,Alenquer M,Roudko V,Chung L,Zheng S,Chang M,Fstkchyan Y,Clohisey S,Dinan AM,Gibbs J,Gifford R,Shen R,Gu Q,Irigoyen N,Campisi L,Huang C,Zhao N,Jones JD,van Knippenberg I,Zhu Z,Moshkina N,Meyer L,Noel J,Peralta Z,Rezelj V,Kaake R,Rosenberg B,Wang B,Wei J,Paessler S,Wise HM,Johnson J,Vannini A,Amorim MJ,Baillie JK,Miraldi ER,Benner C,Brierley I,Digard P,Łuksza M,Firth AE,Krogan N,Greenbaum BD,MacLeod MK,van Bakel H,Garcìa-Sastre A,Yewdell JW,Hutchinson E,Marazzi I
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Thu Jun 25 00:00:00 EDT 2020
An Integrated Epigenomic and Transcriptomic Map of Mouse and Human αβ T Cell Development.
Immunity
Chopp LB,Gopalan V,Ciucci T,Ruchinskas A,Rae Z,Lagarde M,Gao Y,Li C,Bosticardo M,Pala F,Livak F,Kelly MC,Hannenhalli S,Bosselut R
45-0691-82 was used in Flow Cytometry to identify mouse and human αβ thymocyte developmental trajectories.
Tue Dec 15 00:00:00 EST 2020
Contact-dependent delivery of IL-2 by dendritic cells to CD4 T cells in the contraction phase promotes their long-term survival.
Protein & cell
Tong D,Zhang L,Ning F,Xu Y,Hu X,Shi Y
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Increase in liver γδ T cells with concurrent augmentation of IFN-β production during the early stages of a mouse model of acute experimental hepatitis B virus infection.
Experimental and therapeutic medicine
Chang L,Wang L,Ling N,Peng H,Chen M
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
Effects of CD4+ T lymphocytes from ovariectomized mice on bone marrow mesenchymal stem cell proliferation and osteogenic differentiation.
Experimental and therapeutic medicine
Shao BY,Wang L,Yu Y,Chen L,Gan N,Huang WM
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Potentiating the Antitumor Activity of Cytotoxic T Cells via the Transmembrane Domain of IGSF4 That Increases TCR Avidity.
Frontiers in immunology
Kim HR,Park JS,Fatima Y,Kausar M,Park JH,Jun CD
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Tue Jul 27 00:00:00 EDT 2021
Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy.
Cell communication and signaling : CCS
Klepsch V,Pommermayr M,Humer D,Brigo N,Hermann-Kleiter N,Baier G
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Tue Jan 14 00:00:00 EST 2020
SLAMF6 deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint.
eLife
Hajaj E,Eisenberg G,Klein S,Frankenburg S,Merims S,Ben David I,Eisenhaure T,Henrickson SE,Villani AC,Hacohen N,Abudi N,Abramovich R,Cohen JE,Peretz T,Veillette A,Lotem M
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Tue Mar 03 00:00:00 EST 2020
Loss of testosterone impairs anti-tumor neutrophil function.
Nature communications
Markman JL,Porritt RA,Wakita D,Lane ME,Martinon D,Noval Rivas M,Luu M,Posadas EM,Crother TR,Arditi M
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Tue Mar 31 00:00:00 EDT 2020
NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer.
Nature communications
Qin G,Wang X,Ye S,Li Y,Chen M,Wang S,Qin T,Zhang C,Li Y,Long Q,Hu H,Shi D,Li J,Zhang K,Zhai Q,Tang Y,Kang T,Lan P,Xie F,Lu J,Deng W
45-0691-82 was used in Flow Cytometry to verify that triple-negative breast cancer (TNBC) has higher PD-L1 expression than other subtypes.
Fri Apr 03 00:00:00 EDT 2020
CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis.
Journal of neuroinflammation
Funk KE,Klein RS
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Thu Jan 31 00:00:00 EST 2019
Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules.
NPJ vaccines
Andersen TK,Huszthy PC,Gopalakrishnan RP,Jacobsen JT,Fauskanger M,Tveita AA,Grødeland G,Bogen B
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Thu Oct 05 00:00:00 EDT 2023
The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis.
Frontiers in pharmacology
Hansel C,Erschfeld S,Baues M,Lammers T,Weiskirchen R,Trautwein C,Kroy DC,Drescher HK
45-0691 was used in Flow cytometry/Cell sorting to investigate the expression profile of inhibitory T cell receptors on CD4 and CD8 T cells in a mouse model of non-alcoholic steatohepatitis.
Wed Sep 30 00:00:00 EDT 2020
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8+ T cells.
Nature cell biology
Ma R,Ji T,Zhang H,Dong W,Chen X,Xu P,Chen D,Liang X,Yin X,Liu Y,Ma J,Tang K,Zhang Y,Peng Y,Lu J,Zhang Y,Qin X,Cao X,Wan Y,Huang B
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8+ T cell responses.
Journal of controlled release : official journal of the Controlled Release Society
Si Y,Wen Y,Kelly SH,Chong AS,Collier JH
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Sat Jul 28 00:00:00 EDT 2018
MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway.
Clinical and experimental immunology
Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Thu Feb 01 00:00:00 EST 2018
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Wed Mar 28 00:00:00 EDT 2018
MAIT cells contribute to protection against lethal influenza infection in vivo.
Nature communications
van Wilgenburg B,Loh L,Chen Z,Pediongco TJ,Wang H,Shi M,Zhao Z,Koutsakos M,Nüssing S,Sant S,Wang Z,D'Souza C,Jia X,Almeida CF,Kostenko L,Eckle SBG,Meehan BS,Kallies A,Godfrey DI,Reading PC,Corbett AJ,McCluskey J,Klenerman P,Kedzierska K,Hinks TSC
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Fri Nov 09 00:00:00 EST 2018
Homoharringtonine induced immune alteration for an Efficient Anti-tumor Response in Mouse Models of Non-small Cell Lung Adenocarcinoma Expressing Kras Mutation.
Scientific reports
Weng TY,Wu HF,Li CY,Hung YH,Chang YW,Chen YL,Hsu HP,Chen YH,Wang CY,Chang JY,Lai MD
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Tue May 29 00:00:00 EDT 2018
Development of a screening strategy for new modulators of T cell receptor signaling and T cell activation.
Scientific reports
Chen EW,Brzostek J,Gascoigne NRJ,Rybakin V
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Tue Jul 03 00:00:00 EDT 2018
Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling.
The Journal of clinical investigation
Ying W,Wollam J,Ofrecio JM,Bandyopadhyay G,El Ouarrat D,Lee YS,Oh DY,Li P,Osborn O,Olefsky JM
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and Fibrosis.
Journal of the American Society of Nephrology : JASN
Chi HH,Hua KF,Lin YC,Chu CL,Hsieh CY,Hsu YJ,Ka SM,Tsai YL,Liu FC,Chen A
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2017
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
14-3-3 Proteins regulate K2P 5.1 surface expression on T lymphocytes.
Traffic (Copenhagen, Denmark)
Fernández-Orth J,Ehling P,Ruck T,Pankratz S,Hofmann MS,Landgraf P,Dieterich DC,Smalla KH,Kähne T,Seebohm G,Budde T,Wiendl H,Bittner S,Meuth SG
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
IRF6 Regulates Alternative Activation by Suppressing PPARγ in Male Murine Macrophages.
Endocrinology
Li C,Ying W,Huang Z,Brehm T,Morin A,Vella AT,Zhou B
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.
Nature communications
Wang Q,Ning H,Peng H,Wei L,Hou R,Hoft DF,Liu J
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2017
Metabolic maintenance of cell asymmetry following division in activated T lymphocytes.
Nature
Verbist KC,Guy CS,Milasta S,Liedmann S,Kamiński MM,Wang R,Green DR
45-0691 was used in Flow cytometry/Cell sorting to investigate the mechanisms that sustain differential cell fates in daughter T cells after activation by an antigen-presenting cell.
Thu Apr 21 00:00:00 EDT 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Mon Aug 15 00:00:00 EDT 2016
Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells.
eLife
Allison KA,Sajti E,Collier JG,Gosselin D,Troutman TD,Stone EL,Hedrick SM,Glass CK
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Mon Jul 04 00:00:00 EDT 2016
miR-150 regulates obesity-associated insulin resistance by controlling B cell functions.
Scientific reports
Ying W,Tseng A,Chang RC,Wang H,Lin YL,Kanameni S,Brehm T,Morin A,Jones B,Splawn T,Criscitiello M,Golding MC,Bazer FW,Safe S,Zhou B
45-0691 was used in Flow cytometry/Cell sorting to demonstrate a role for miR-150 in regulating B cell functions in adipose tissue.
Mon Feb 01 00:00:00 EST 2016
MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.
The Journal of clinical investigation
Ying W,Tseng A,Chang RC,Morin A,Brehm T,Triff K,Nair V,Zhuang G,Song H,Kanameni S,Wang H,Golding MC,Bazer FW,Chapkin RS,Safe S,Zhou B
45-0691 was used in Flow cytometry/Cell sorting to investigate the regulatory network of polarised activation of adipose tissue macrophages.
Mon Nov 02 00:00:00 EST 2015
Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells.
Frontiers in immunology
Vogel AJ,Brown DM
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Fri Jul 10 00:00:00 EDT 2015
Diverse roles for T-bet in the effector responses required for resistance to infection.
Journal of immunology (Baltimore, Md. : 1950)
Harms Pritchard G,Hall AO,Christian DA,Wagage S,Fang Q,Muallem G,John B,Glatman Zaretsky A,Dunn WG,Perrigoue J,Reiner SL,Hunter CA
45-0691 was used in Flow cytometry/Cell sorting to highlight T-bet-independent pathways to IFN-γ production and reveal a novel role for this transcription factor in coordinating the T cell responses necessary to control infection in peripheral tissues.
Sun Feb 01 00:00:00 EST 2015
MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation.
Stem cell reports
Tan Y,AlKhamees B,Jia D,Li L,Couture JF,Figeys D,Jinushi M,Wang L
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Tue Nov 10 00:00:00 EST 2015
Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.
Oncoimmunology
Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
H9N2 influenza whole inactivated virus combined with polyethyleneimine strongly enhances mucosal and systemic immunity after intranasal immunization in mice.
Clinical and vaccine immunology : CVI
Qin T,Yin Y,Huang L,Yu Q,Yang Q
45-0691 was used in Flow cytometry/Cell sorting to investigate the immune activity of polyethyleneimine with H9N2 influenza whole inactivated virus, showing that it enhances mucosal and systemic immunity after intranasal immunization.
Wed Apr 01 00:00:00 EDT 2015
Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development.
Nature immunology
Au-Yeung BB,Melichar HJ,Ross JO,Cheng DA,Zikherman J,Shokat KM,Robey EA,Weiss A
45-0691 was used in Flow cytometry/Cell sorting to show that CD4(+)CD8(+) thymocytes integrate multiple, transient, Zap70-dependent signals over more than 36 h to reach a cumulative threshold for positive selection.
Tue Jul 01 00:00:00 EDT 2014
mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function.
Journal of immunology (Baltimore, Md. : 1950)
Donnelly RP,Loftus RM,Keating SE,Liou KT,Biron CA,Gardiner CM,Finlay DK
45-0691 was used in Flow cytometry/Cell sorting to investigate whether mTORC1-controlled metabolism underpins normal natural killer cell proinflammatory functions.
Sat Nov 01 00:00:00 EDT 2014
Differential requirement for CCR4 and CCR7 during the development of innate and adaptive αβT cells in the adult thymus.
Journal of immunology (Baltimore, Md. : 1950)
Cowan JE,McCarthy NI,Parnell SM,White AJ,Bacon A,Serge A,Irla M,Lane PJ,Jenkinson EJ,Jenkinson WE,Anderson G
45-0691 was used in Flow cytometry/Cell sorting to identify novel roles for CCR7 during intrathymic T cell development, highlighting its importance in enabling multiple αβT cell lineages to access the thymic medulla.
Fri Aug 01 00:00:00 EDT 2014
Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock.
PloS one
Hou H,Liu W,Wu S,Lu Y,Peng J,Zhu Y,Lu Y,Wang F,Sun Z
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Mon Jul 06 00:00:00 EDT 2015
The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development.
The Journal of experimental medicine
Cowan JE,Parnell SM,Nakamura K,Caamano JH,Lane PJ,Jenkinson EJ,Jenkinson WE,Anderson G
45-0691 was used in Flow cytometry/Cell sorting to demonstrate a differential requirement for the thymic medulla in relation to CD4 conventional and Foxp3(+) thymocyte lineages.
Mon Apr 08 00:00:00 EDT 2013
Gr1(int)CD11b+ myeloid-derived suppressor cells in Mycobacterium tuberculosis infection.
PloS one
Obregón-Henao A,Henao-Tamayo M,Orme IM,Ordway DJ
45-0691 was used in Immunofluorescence to compare the bacterial burden, lung pathology and Gr1(int)CD11b(+) myeloid-derived suppressor cell immune responses in M. tuberculosis infected mice.
Fri Jun 20 00:00:00 EDT 2014
Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla.
Journal of immunology (Baltimore, Md. : 1950)
Desanti GE,Cowan JE,Baik S,Parnell SM,White AJ,Penninger JM,Lane PJ,Jenkinson EJ,Jenkinson WE,Anderson G
45-0691 was used in Flow cytometry/Cell sorting to study how multiple hemopoietic cell types regulate mTEC development through differential provision of RANKL/CD40L during ontogeny, revealing molecular differences in foetal and adult hemopoietic cross-talk.
Sat Dec 15 00:00:00 EST 2012
The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin.
PloS one
Qi Y,Operario DJ,Georas SN,Mosmann TR
45-0691 was used in Flow cytometry/Cell sorting to collate a detailed analysis of the regulation of Amphiregulin expression by human T cell subsets.
Thu Dec 13 00:00:00 EST 2012
Combination treatment of mice with CRx-153 (nortriptyline and desloratadine) decreases the severity of experimental autoimmune encephalomyelitis.
Cellular immunology
Podojil JR,Padval MV,Miller SD
45-0691 was used in Flow cytometry/Cell sorting to determine if treatment of PLP(139-151)-induced R-EAE with a combination of two drugs decreases R-EAE disease.
Fri Oct 14 00:00:00 EDT 2011
Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway.
Aging cell
Lages CS,Lewkowich I,Sproles A,Wills-Karp M,Chougnet C
45-0691 was used in Flow cytometry/Cell sorting to suggest that blockade of the PD-1/PD-L1 is not likely to be efficient at restoring exhausted T-cell responses in aged hosts.
Fri Oct 01 00:00:00 EDT 2010
Modulation of naive CD4+ T-cell responses to an airway antigen during pulmonary mycobacterial infection.
Infection and immunity
Anis MM,Fulton SA,Reba SM,Harding CV,Boom WH
Published figure using CD69 monoclonal antibody (Product # 45-0691-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2007