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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1/IgG2a|
|Immunogen||T-acute lymphoblastic leukemia (T-ALL) cells|
|Conjugate||FITC , PE|
|Storage buffer||PBS with 0.2% carrier protein|
|Contains||0.08% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is a monoclonal mixture of FITC-conjugated CD7 (clone MG34, isotype IgG2a) and PE-conjugated CD13 (clone E735, isotype IgG1).
CD7 is a 40kD transmembrane, single-chain glycoprotein. CD7 is expressed by majority of peripheral blood T cells, NK cells and all Thymocytes. The presence or absence of CD7 is a useful marker for the classification of T- and NK-cell malignancies. The CD7 molecule is absent in a subset of human T cells under certain physiologic conditions. Thus an increase in CD7 negative T cells can be seen in some inflammatory skin disease. This antibody recognizes the human CD13 cell surface glycoprotein, a 150kD molecule expressed by granulocytes and monocytes, and by myeloid leukemia cells. Inhibits infection of cells by human coronavirus, inhibits aminopeptidase N activity of the CD13 molecule immunoprecipitates. MA1-22542 detects CD13 in Human samples.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
alanyl (membrane) aminopeptidase; alanyl aminopeptidase; aminopeptidase M; aminopeptidase N; aminopeptidase N/CD13; ANPEP; AP-M; AP-N; Apn; Cd13; CD7 antigen (p41); hAPN; LEU-9; membrane alanyl aminopeptidase; membrane protein p161; microsomal aminopeptidase; myeloid plasma membrane glycoprotein CD13; p41 protein; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40
ANPEP; APN; CD13; CD7; GP150; GP40; LAP1; LEU-9; P150; PEPN; Tp40; TP41