|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from N-terminus region of human CD79a protein|
|Storage buffer||tissue culture supernatant diluted in TBS, pH 7.6, with 1% BSA|
|Contains||<0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:100|
|Immunohistochemistry (Paraffin) (IHC (P))||Ready-to-use|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with monkey, equine, bovine, porcine, rabbit, guinea pig, and chicken based on sequence homology.
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is tonsil or B cell lymphoma.
A disulphide-linked heterodimer, consisting of CD79a / mb-1 and CD79b / B29 polypeptides, is non-covalently associated with membrane-bound
immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it
is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas,
and in some myelomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Liquid-based cytologic findings of solitary extramedullary plasmacytoma in thyroid: a case report identified with fine-needle aspiration cytology.
MA1-39569 was used in immunocytochemistry to report on a case of solitary extramedullary plasmacytoma of the thyroid
|Lee CH,Jung YY,Chung YR,Ryu HS||Diagnostic cytopathology (42:964)||2014|
Composite lymphoma in the anterior mediastinum: a case report and review of the literature.
MA1-39569 was used in immunohistochemistry to present a case report of an unusual composite lymphoma in the mediastinum
|Yu G,Kong L,Qu G,Zhang Q,Wang W,Jiang L||Diagnostic pathology (6:null)||2011|
Identification of rare Epstein-Barr virus infected memory B cells and plasma cells in non-monomorphic post-transplant lymphoproliferative disorders and the signature of viral signaling.
MA1-39569 was used in immunohistochemistry to investigate the role of Epstein-Barr virus infection in the immune response of non-monomorphic post-transplant lymphoproliferative disorders
|Shaknovich R,Basso K,Bhagat G,Mansukhani M,Hatzivassiliou G,Murty VV,Buettner M,Niedobitek G,Alobeid B,Cattoretti G||Haematologica (91:1313)||2006|
Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells.
MA1-39569 was used in immunohistochemistry to investigate Intracellular distribution of activation-induced cytidine deaminase in extrafollicular and germinal center B cells
|Cattoretti G,Büttner M,Shaknovich R,Kremmer E,Alobeid B,Niedobitek G||Blood (107:3967)||2006|
PRDM1/Blimp-1 is expressed in human B-lymphocytes committed to the plasma cell lineage.
MA1-39569 was used in immunohistochemistry to study the role of PRDM1/Blimp-1 in human B-lymphocyte differentiation
|Cattoretti G,Angelin-Duclos C,Shaknovich R,Zhou H,Wang D,Alobeid B||The Journal of pathology (206:76)||2005|