|Tested species reactivity||Human, Mouse|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from N-terminal region of human CD79a protein|
|Storage buffer||tissue culture supernatant|
|Contains||15mM sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:2|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:300|
|Western Blot (WB)||1:1000-1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-14556 targets CD79a in IHC (P), WB and FACS applications and shows reactivity with Human and Mouse samples.
The MA5-14556 immunogen is synthetic peptide derived from N-terminal region of human CD79a protein.
A disulphide-linked heterodimer, consisting of CD79a/mb-1 and CD79b/B29 polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Liquid-based cytologic findings of solitary extramedullary plasmacytoma in thyroid: a case report identified with fine-needle aspiration cytology.
MA5-14556 was used in immunocytochemistry to report on a case of solitary extramedullary plasmacytoma of the thyroid
|Lee CH,Jung YY,Chung YR,Ryu HS||Diagnostic cytopathology (42:964)||2014|
Composite lymphoma in the anterior mediastinum: a case report and review of the literature.
MA5-14556 was used in immunohistochemistry to present a case report of an unusual composite lymphoma in the mediastinum
|Yu G,Kong L,Qu G,Zhang Q,Wang W,Jiang L||Diagnostic pathology (6:null)||2011|
Identification of rare Epstein-Barr virus infected memory B cells and plasma cells in non-monomorphic post-transplant lymphoproliferative disorders and the signature of viral signaling.
MA5-14556 was used in immunohistochemistry to investigate the role of Epstein-Barr virus infection in the immune response of non-monomorphic post-transplant lymphoproliferative disorders
|Shaknovich R,Basso K,Bhagat G,Mansukhani M,Hatzivassiliou G,Murty VV,Buettner M,Niedobitek G,Alobeid B,Cattoretti G||Haematologica (91:1313)||2006|
Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells.
MA5-14556 was used in immunohistochemistry to investigate Intracellular distribution of activation-induced cytidine deaminase in extrafollicular and germinal center B cells
|Cattoretti G,Büttner M,Shaknovich R,Kremmer E,Alobeid B,Niedobitek G||Blood (107:3967)||2006|
PRDM1/Blimp-1 is expressed in human B-lymphocytes committed to the plasma cell lineage.
MA5-14556 was used in immunohistochemistry to study the role of PRDM1/Blimp-1 in human B-lymphocyte differentiation
|Cattoretti G,Angelin-Duclos C,Shaknovich R,Zhou H,Wang D,Alobeid B||The Journal of pathology (206:76)||2005|