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|Tested species reactivity||Rabbit|
|Published species reactivity||Rabbit|
|Host / Isotype||Mouse / IgG1|
|Storage buffer||PBS, pH 7.4|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1/100 - 1/200|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Two alternative transcripts encoding distinct isoforms, one membrane associated and one secreted, have been identified [Gene Wiki: CD8a].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Kinetics of immune cell infiltration in vaccinia virus keratitis.
MA1-82699 was used in immunohistochemistry to study the immune cells in corneas in vaccinia virus keratitis
|Altmann S,Toomey M,Nesbit B,McIntyre K,Covert J,Dubielzig RR,Leatherberry G,Adkins E,Murphy CJ,Brandt CR||Investigative ophthalmology & visual science (51:4541)||2010|