|Flow Cytometry (Flow)||1:40|
|Tested Species reactivity||Chicken|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||pDNA encoding chicken CD80 followed by CD80-Ig fusion protein.|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred|
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B7-1; B7.1; Cd28l; CD28LG; CD28LG1; CD80 antigen; CD80 molecule; LAB7; Ly-53; Ly53; MIC17; TS/A-1
Gene Aliases: RCJMB04_15k1
Entrez Gene ID: (Chicken) 768950
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