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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||MOLT-4 (human T-ALL cell line)|
|Storage buffer||PBS, pH 7.4|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells - e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
26 kDa cell surface protein TAPA-1; CD81 antigen (target of antiproliferative antibody 1); target of antiproliferative antibody 1; tetraspanin-28; tspan-28
CD81; CVID6; S5.7; TAPA1; TSPAN28