Product References
Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern.
Communications biology
Tabariès S,Annis MG,Lazaris A,Petrillo SK,Huxham J,Abdellatif A,Palmieri V,Chabot J,Johnson RM,Van Laere S,Verhoef C,Hachem Y,Yumeen S,Meti N,Omeroglu A,Altinel G,Gao ZH,Yu ASL,Grünhagen DJ,Vermeulen P,Metrakos P,Siegel PM
10630D was used in Western Blot to provide evidence that Claudin-2 status in patient-derived extracellular vesicles may serve as a relevant prognostic biomarker to predict whether colorectal cancer patients have developed replacement type liver metastases.
Wed Jun 02 00:00:00 EDT 2021
Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern.
Communications biology
Tabariès S,Annis MG,Lazaris A,Petrillo SK,Huxham J,Abdellatif A,Palmieri V,Chabot J,Johnson RM,Van Laere S,Verhoef C,Hachem Y,Yumeen S,Meti N,Omeroglu A,Altinel G,Gao ZH,Yu ASL,Grünhagen DJ,Vermeulen P,Metrakos P,Siegel PM
10630D was used in Western Blot to provide evidence that Claudin-2 status in patient-derived extracellular vesicles may serve as a relevant prognostic biomarker to predict whether colorectal cancer patients have developed replacement type liver metastases.
Wed Jun 02 00:00:00 EDT 2021
Mesenchymal growth hormone receptor deficiency leads to failure of alveolar progenitor cell function and severe pulmonary fibrosis.
Science advances
Xie T,Kulur V,Liu N,Deng N,Wang Y,Rowan SC,Yao C,Huang G,Liu X,Taghavifar F,Liang J,Hogaboam C,Stripp B,Chen P,Jiang D,Noble PW
10630D was used in Western Blot to demonstrate a previously unidentified mesenchymal paracrine signaling coordinated by GHR that is capable of supporting ATII progenitor cell renewal and limiting the severity of lung fibrosis.
Tue Jun 01 00:00:00 EDT 2021
Curcumin-primed human BMSC-derived extracellular vesicles reverse IL-1β-induced catabolic responses of OA chondrocytes by upregulating miR-126-3p.
Stem cell research & therapy
Li S,Stöckl S,Lukas C,Herrmann M,Brochhausen C,König MA,Johnstone B,Grässel S
10630D was used in Western Blotting to evaluate modulatory effects of curcumin-primed human (h)BMSC-derived EVs (Cur-EVs) on IL-1β stimulated human osteoarthritic chondrocytes (OA-CH).
Thu Apr 29 00:00:00 EDT 2021
Curcumin-primed human BMSC-derived extracellular vesicles reverse IL-1β-induced catabolic responses of OA chondrocytes by upregulating miR-126-3p.
Stem cell research & therapy
Li S,Stöckl S,Lukas C,Herrmann M,Brochhausen C,König MA,Johnstone B,Grässel S
10630D was used in Western Blotting to evaluate modulatory effects of curcumin-primed human (h)BMSC-derived EVs (Cur-EVs) on IL-1β stimulated human osteoarthritic chondrocytes (OA-CH).
Thu Apr 29 00:00:00 EDT 2021
Extracellular Vesicle Surface Signatures in IPF Patients: A Multiplex Bead-Based Flow Cytometry Approach.
Cells
d'Alessandro M,Soccio P,Bergantini L,Cameli P,Scioscia G,Foschino Barbaro MP,Lacedonia D,Bargagli E
10630D was used in Western Blotting to evaluate the expression of exosomal surface epitopes in a cohort of idiopathic pulmonary fibrosis (IPF) patients followed in two Italian Referral Centres for Interstitial Lung Diseases, comparing them with a group of healthy volunteers.
Wed Apr 28 00:00:00 EDT 2021
Extracellular Vesicle Surface Signatures in IPF Patients: A Multiplex Bead-Based Flow Cytometry Approach.
Cells
d'Alessandro M,Soccio P,Bergantini L,Cameli P,Scioscia G,Foschino Barbaro MP,Lacedonia D,Bargagli E
10630D was used in Western Blotting to evaluate the expression of exosomal surface epitopes in a cohort of idiopathic pulmonary fibrosis (IPF) patients followed in two Italian Referral Centres for Interstitial Lung Diseases, comparing them with a group of healthy volunteers.
Wed Apr 28 00:00:00 EDT 2021
Influence of Extracellular Vesicles Isolated From Osteoblasts of Patients With Cox-Arthrosis and/or Osteoporosis on Metabolism and Osteogenic Differentiation of BMSCs.
Frontiers in bioengineering and biotechnology
Niedermair T,Lukas C,Li S,Stöckl S,Craiovan B,Brochhausen C,Federlin M,Herrmann M,Grässel S
10630D was used in Western Blotting to show that EVs isolated from osteoblasts of patients with hip OA (coxarthrosis/CA), osteoporosis (OP), or a combination of both (CA/OP) might negatively affect metabolism and osteogenic differentiation of bone-marrow derived (B)MSCs.
Tue Jan 12 00:00:00 EST 2021
hBMSC-Derived Extracellular Vesicles Attenuate IL-1β-Induced Catabolic Effects on OA-Chondrocytes by Regulating Pro-inflammatory Signaling Pathways.
Frontiers in bioengineering and biotechnology
Li S,Stöckl S,Lukas C,Götz J,Herrmann M,Federlin M,Grässel S
10630D was used in Western Blotting to investigate putative protective effects of hBMSC-derived EVs as a cell-free approach, on IL-1β-stimulated chondrocytes obtained from OA-patients.
Tue Jan 12 00:00:00 EST 2021
hnRNPA2B1 inhibits the exosomal export of miR-503 in endothelial cells.
Cellular and molecular life sciences : CMLS
Pérez-Boza J,Boeckx A,Lion M,Dequiedt F,Struman I
10630D was used in Western Blotting to understand the mechanisms of chemotherapeutic drug epirubicin increasing the exosomal export of miR-503 in endothelial cells.
Sun Nov 01 00:00:00 EDT 2020
Characterization and internalization of small extracellular vesicles released by human primary macrophages derived from circulating monocytes.
PloS one
Arteaga-Blanco LA,Mojoli A,Monteiro RQ,Sandim V,Menna-Barreto RFS,Pereira-Dutra FS,Bozza PT,Resende RO,Bou-Habib DC
10630D was used in Western Blotting to aim to provide an alternative protocol based on differential ultracentrifugation (dUC) to describe small EVs (sEVs) from these cells.
Wed Oct 14 00:00:00 EDT 2020
Characterization and internalization of small extracellular vesicles released by human primary macrophages derived from circulating monocytes.
PloS one
Arteaga-Blanco LA,Mojoli A,Monteiro RQ,Sandim V,Menna-Barreto RFS,Pereira-Dutra FS,Bozza PT,Resende RO,Bou-Habib DC
10630D was used in Western Blotting to aim to provide an alternative protocol based on differential ultracentrifugation (dUC) to describe small EVs (sEVs) from these cells.
Wed Oct 14 00:00:00 EDT 2020
Serum small extracellular vesicle-derived LINC00853 as a novel diagnostic marker for early hepatocellular carcinoma.
Molecular oncology
Kim SS,Baek GO,Ahn HR,Sung S,Seo CW,Cho HJ,Nam SW,Cheong JY,Eun JW
10630D was used in Western Blotting to identify novel long noncoding RNA (lncRNA) biomarkers for hepatocellular carcinoma (HCC) using publicly available tissue genomic datasets and validate their diagnostic utility for early-stage HCC.
Thu Oct 01 00:00:00 EDT 2020
Human induced pluripotent stem cells ameliorate hyperoxia-induced lung injury in a mouse model.
American journal of translational research
Mitchell A,Wanczyk H,Jensen T,Finck C
10630D was used in Western Blotting to determine if iPSCs and diPSCs could repair hyperoxia-induced lung damage in a mouse model.
Mon Sep 28 00:00:00 EDT 2020
Evidence that dysplasia related microRNAs in Barrett's esophagus target PD-L1 expression and contribute to the development of esophageal adenocarcinoma.
Aging
Xu J,Yin Z,Yang L,Wu F,Fan J,Huang Q,Jin Y,Yang G
10630D was used in Western Blotting to characterize miRNA content of exosomes in both Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) patients.
Wed Sep 09 00:00:00 EDT 2020
Evidence that dysplasia related microRNAs in Barrett's esophagus target PD-L1 expression and contribute to the development of esophageal adenocarcinoma.
Aging
Xu J,Yin Z,Yang L,Wu F,Fan J,Huang Q,Jin Y,Yang G
10630D was used in Western Blotting to characterize miRNA content of exosomes in both Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) patients.
Wed Sep 09 00:00:00 EDT 2020
Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles.
Journal of extracellular vesicles
Whittaker TE,Nagelkerke A,Nele V,Kauscher U,Stevens MM
10630D was used in Dot blot to investigate the relative contribution of extracellular vesicles in in vitro models for angiogenesis and wound healing.
Wed Aug 26 00:00:00 EDT 2020
Osteosarcoma-Derived Extracellular Vesicles Induce Lung Fibroblast Reprogramming.
International journal of molecular sciences
Mazumdar A,Urdinez J,Boro A,Migliavacca J,Arlt MJE,Muff R,Fuchs B,Snedeker JG,Gvozdenovic A
Published figure using CD81 monoclonal antibody (Product # 10630D) in Flow Cytometry
Thu Jul 30 00:00:00 EDT 2020
Osteosarcoma-Derived Extracellular Vesicles Induce Lung Fibroblast Reprogramming.
International journal of molecular sciences
Mazumdar A,Urdinez J,Boro A,Migliavacca J,Arlt MJE,Muff R,Fuchs B,Snedeker JG,Gvozdenovic A
Published figure using CD81 monoclonal antibody (Product # 10630D) in Flow Cytometry
Thu Jul 30 00:00:00 EDT 2020
Detection of Viral RNA Fragments in Human iPSC-Cardiomyocytes following Treatment with Extracellular Vesicles from SARS-CoV-2 Coding-Sequence-Overexpressing Lung Epithelial Cells.
bioRxiv : the preprint server for biology
Kwon Y,Nukala SB,Srivastava S,Miyamoto H,Ismail NI,Rehman J,Ong SB,Lee WH,Ong SG
10630D was used in Western Blotting to demonstrate that SARS-CoV-2 RNA-containing extracellular vesicles represent an indirect route of viral RNA entry into human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs).
Wed Jul 01 00:00:00 EDT 2020
Molecular imaging of extracellular vesicles in vitro via Raman metabolic labelling.
Journal of materials chemistry. B
Horgan CC,Nagelkerke A,Whittaker TE,Nele V,Massi L,Kauscher U,Penders J,Bergholt MS,Hood SR,Stevens MM
10630D was used in Dot blot to enable a deeper understanding of many of the biological mechanisms underpinning EVs, with profound implications for the design of EVs as therapeutic delivery vectors and applications as disease biomarkers.
Wed May 27 00:00:00 EDT 2020
The Potential of CD16 on Plasma-Derived Exosomes as a Liquid Biomarker in Head and Neck Cancer.
International journal of molecular sciences
Hofmann L,Ludwig S,Schuler PJ,Hoffmann TK,Brunner C,Theodoraki MN
10630D was used in Western Blotting to demonstrate that exosomes have the potential to serve as easily accessible, non-invasive biomarkers for tumor status and tumor aggressiveness as well as for the degree of immune suppression in HNSCC patients.
Tue May 26 00:00:00 EDT 2020
The Potential of CD16 on Plasma-Derived Exosomes as a Liquid Biomarker in Head and Neck Cancer.
International journal of molecular sciences
Hofmann L,Ludwig S,Schuler PJ,Hoffmann TK,Brunner C,Theodoraki MN
10630D was used in Western Blotting to demonstrate that exosomes have the potential to serve as easily accessible, non-invasive biomarkers for tumor status and tumor aggressiveness as well as for the degree of immune suppression in HNSCC patients.
Tue May 26 00:00:00 EDT 2020
Gold Nanocluster Extracellular Vesicle Supraparticles: Self-Assembled Nanostructures for Three-Dimensional Uptake Visualization.
Langmuir : the ACS journal of surfaces and colloids
Kauscher U,Penders J,Nagelkerke A,Holme MN,Nele V,Massi L,Gopal S,Whittaker TE,Stevens MM
10630D was used in Dot blot to show that extracellular vesicles combined with hydrophobic gold nanoclusters (AuNCs) can self-assemble into supraparticles.
Tue Apr 14 00:00:00 EDT 2020
MicroRNAs in Tumor Exosomes Drive Immune Escape in Melanoma.
Cancer immunology research
Vignard V,Labbé M,Marec N,André-Grégoire G,Jouand N,Fonteneau JF,Labarrière N,Fradin D
10630D was used in Western Blotting to suggest that miRNAs in melanoma-derived exosomes aid tumor immune evasion and could be a therapeutic target.
Sat Feb 01 00:00:00 EST 2020
Tumor-derived exosomes educate fibroblasts to promote salivary adenoid cystic carcinoma metastasis via NGF-NTRK1 pathway.
Oncology letters
Xu Z,Zheng X,Zheng J
10630D was used in Western Blotting to demonstrate that SACC-83 cell-derived exosomes educated HPLF cells toward the protumorigenic phenotype via the NGF-NTRK1 pathway.
Tue Oct 01 00:00:00 EDT 2019
Harmonization of exosome isolation from culture supernatants for optimized proteomics analysis.
PloS one
Abramowicz A,Marczak L,Wojakowska A,Zapotoczny S,Whiteside TL,Widlak P,Pietrowska M
Published figure using CD81 monoclonal antibody (Product # 10630D) in Western Blot
Thu Apr 04 00:00:00 EDT 2019
Leukemia-derived exosomes and cytokines pave the way for entry into the brain.
Journal of leukocyte biology
Kinjyo I,Bragin D,Grattan R,Winter SS,Wilson BS
Published figure using CD81 monoclonal antibody (Product # 10630D) in Western Blot
Mon Apr 01 00:00:00 EDT 2019
Leukemia-derived exosomes and cytokines pave the way for entry into the brain.
Journal of leukocyte biology
Kinjyo I,Bragin D,Grattan R,Winter SS,Wilson BS
Published figure using CD81 monoclonal antibody (Product # 10630D) in Western Blot
Mon Apr 01 00:00:00 EDT 2019
Suppressive effect of an analog of the antimicrobial peptide of LL‑37 on colon cancer cells via exosome‑encapsulated miRNAs.
International journal of molecular medicine
Hayashi M,Kuroda K,Ihara K,Iwaya T,Isogai E
10630D was used in Western Blotting to analyse the exosomes released by HCT116 cells treated with FF/CAP18.
Sat Dec 01 00:00:00 EST 2018
Helicobacter pylori-induced exosomal MET educates tumour-associated macrophages to promote gastric cancer progression.
Journal of cellular and molecular medicine
Che Y,Geng B,Xu Y,Miao X,Chen L,Mu X,Pan J,Zhang C,Zhao T,Wang C,Li X,Wen H,Liu Z,You Q
Published figure using CD81 monoclonal antibody (Product # 10630D) in Western Blot
Thu Nov 01 00:00:00 EDT 2018
Exploring the RNA landscape of endothelial exosomes.
RNA (New York, N.Y.)
Pérez-Boza J,Lion M,Struman I
10630D was used in Western Blotting to characterise the RNA composition of healthy endothelial cells and exosomes to provide an accurate profile of the different coding and noncoding RNA species found per compartment.
Thu Mar 01 00:00:00 EST 2018
Microvesicle-mediated delivery of miR-1343: impact on markers of fibrosis.
Cell and tissue research
Stolzenburg LR,Harris A
Published figure using CD81 monoclonal antibody (Product # 10630D) in Western Blot
Thu Feb 01 00:00:00 EST 2018
Exosomal MicroRNA-15a Transfer from the Pancreas Augments Diabetic Complications by Inducing Oxidative Stress.
Antioxidants & redox signaling
Kamalden TA,Macgregor-Das AM,Kannan SM,Dunkerly-Eyring B,Khaliddin N,Xu Z,Fusco AP,Yazib SA,Chow RC,Duh EJ,Halushka MK,Steenbergen C,Das S
10630D was used in Western Blotting to determine the role of exosomal miRNA during type 2 diabetes.
Wed Nov 01 00:00:00 EDT 2017
REG3β modifies cell tumor function by impairing extracellular vesicle uptake.
Scientific reports
Bonjoch L,Gironella M,Iovanna JL,Closa D
Published figure using CD81 monoclonal antibody (Product # 10630D) in Western Blot
Fri Jun 09 00:00:00 EDT 2017
SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling.
Molecular and cellular biology
Draber P,Vonkova I,Stepanek O,Hrdinka M,Kucova M,Skopcova T,Otahal P,Angelisova P,Horejsi V,Yeung M,Weiss A,Brdicka T
10630D was used in Western Blotting to suggest that SCIMP is involved in signal transduction after major histocompatibility complex type II stimulation and regulates antigen presentation and other antigen-presenting cell functions.
Tue Nov 01 00:00:00 EDT 2011
Caspase-1 activation of caspase-6 in human apoptotic neurons.
Cell death and differentiation
Guo H,Pétrin D,Zhang Y,Bergeron C,Goodyer CG,LeBlanc AC
10630D was used in western blot to study the activation of caspase-6 in human apoptotic neurons by caspase-1
Wed Feb 01 00:00:00 EST 2006
