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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||B-lymphoblastoid cell line ARH 77|
|Conjugate||PE-Alexa Fluor® 700|
|Storage buffer||PBS with BSA, sucrose|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.
Analyte Specific Reagent
B-lymphocyte activation antigen B7-2, BU63, CD86 antigen (CD28 antigen ligand 2, B7-2 antigen), CTLA-4 counter-receptor B7.2, FUN-1, B7-2, B7.2, CD28LG2, LAB72, MGC34413, B-lymphocyte antigen B7-2, B7-2 antigen, CD28 antigen ligand 2
B7-2, LAB72, CD28LG2, B7.2, B70