|Tested species reactivity||Human|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Storage buffer||PBS with 1% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:20|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Major histocompatibility complex class II (DR) antigen and costimulatory molecules on in vitro and in vivo activated human polymorphonuclear neutrophils.
MA1-35969 was used in flow cytometry and immunocytochemistry to compare X-L of Mac -1 with other neutrophil activators
|Sandilands GP,McCrae J,Hill K,Perry M,Baxter D||Immunology (119:562)||2006|
|Not Applicable||3.3 µg/ml||
Profiling dendritic cell maturation with dedicated microarrays.
MA1-35969 was used in flow cytometry to develop a dendritic cell-dedicated microarray
|McIlroy D,Tanguy-Royer S,Le Meur N,Guisle I,Royer PJ,Léger J,Meflah K,Grégoire M||Journal of leukocyte biology (78:794)||2005|
|Not Applicable||Not Cited||
Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions.
MA1-35969 was used in flow cytometry to report that OX40 ligand is selectively induced by IL-2, IL-12, or IL-15-activated human NK cells following stimulation through NKG2D
|Zingoni A,Sornasse T,Cocks BG,Tanaka Y,Santoni A,Lanier LL||Journal of immunology (Baltimore, Md. : 1950) (173:3716)||2004|
Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus.
MA1-35969 was used in flow cytometry to report that CD34(+) progenitor cell-derived Langerhans cells-type DCs exhibit a differentiation state-dependent susceptibility to CMV infection.
|Hertel L,Lacaille VG,Strobl H,Mellins ED,Mocarski ES||Journal of virology (77:7563)||2003|
CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties.
MA1-35969 was used in flow cytometry to elucidate the importance of C domains in the functioning of CD80 and CD86.
|Vasu C,Wang A,Gorla SR,Kaithamana S,Prabhakar BS,Holterman MJ||International immunology (15:167)||2003|
CD40 ligand-stimulated B cell precursor leukemic cells elicit interferon-gamma production by autologous bone marrow T cells in childhood acute lymphoblastic leukemia.
MA1-35969 was used in flow cytometry to test if CD40L activates the antigen-presenting cell capacity of B cell precursor acute lymphoblastic leukemia cells.
|Todisco E,Gaipa G,Biagi E,Bonamino M,Gramigna R,Introna M,Biondi A||Leukemia (16:2046)||2002|
Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.
MA1-35969 was used in flow cytometry to characterize CD4(+)CD25(+) human T cells.
|Ng WF,Duggan PJ,Ponchel F,Matarese G,Lombardi G,Edwards AD,Isaacs JD,Lechler RI||Blood (98:2736)||2001|