|Tested species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Rat / IgG2b|
|Immunogen||Mouse thymus or spleen|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1 µg/10^6 cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 2 publications below|
CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. It is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. Thy 1 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Stimulation of macrophage Fc gamma RIIIA activates the receptor-associated protein tyrosine kinase Syk and induces phosphorylation of multiple proteins including p95Vav and p62/GAP-associated protein.
A14728 was used in flow cytometry to study the role of tyrosine phosphorylation during signal transduction by the phagocytic macrophage FcR Fc gamma RIIIA.
|Darby C,Geahlen RL,Schreiber AD||Journal of immunology (Baltimore, Md. : 1950) (152:5429)||1994|
Small cortical thymocytes are subject to positive selection.
A14728 was used in flow cytometry to identify the developmental stages where positive selection is needed for mature T cell production.
|Lundberg K,Shortman K||The Journal of experimental medicine (179:1475)||1994|