|Tested species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Mouse / IgG2b|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1.0 ug/10^6 cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 9 publications below|
MA5-17748 targets CD90/Thy-1 in FACS applications and shows reactivity with Mouse samples.
The MA5-17748 immunogen is cBA/J.
Thy-1 or CD90 is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of Thy-1 lead to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Immunogenicity of undifferentiated and differentiated allogeneic mouse mesenchymal stem cells.
MA5-17748 was used in flow cytometry to study the immunogenicity and immunomodulatory properties of bone marrow-derived mesenchymal stem cells using an allogeneic mouse model.
|Mukonoweshuro B,Brown CJ,Fisher J,Ingham E||Journal of tissue engineering (5:null)||2014|
Development and functional analysis of eosinophils from murine embryonic stem cells.
MA5-17748 was used in flow cytometry to generate and characterize eosinophils from murine embryonic stem cells.
|Hamaguchi-Tsuru E,Nobumoto A,Hirose N,Kataoka S,Fujikawa-Adachi K,Furuya M,Tominaga A||British journal of haematology (124:819)||2004|
Immature multipotent hemopoietic progenitors lacking long-term bone marrow-reconstituting activity in the aorta-gonad-mesonephros region of murine day 10 fetuses.
MA5-17748 was used in flow cytometry to examine multipotent progenitors from early fetuses.
|Ohmura K,Kawamoto H,Lu M,Ikawa T,Ozaki S,Nakao K,Katsura Y||Journal of immunology (Baltimore, Md. : 1950) (166:3290)||2001|
Emergence of T, B, and myeloid lineage-committed as well as multipotent hemopoietic progenitors in the aorta-gonad-mesonephros region of day 10 fetuses of the mouse.
MA5-17748 was used in flow cytometry to investigate the aorta-gonad-mesonephros region as a source of hemopoietic progenitors.
|Ohmura K,Kawamoto H,Fujimoto S,Ozaki S,Nakao K,Katsura Y||Journal of immunology (Baltimore, Md. : 1950) (163:4788)||1999|
Emergence of T cell progenitors without B cell or myeloid differentiation potential at the earliest stage of hematopoiesis in the murine fetal liver.
MA5-17748 was used in flow cytometry to assess if progenitors colonizing the thymus are T cell lineage restricted.
|Kawamoto H,Ohmura K,Fujimoto S,Katsura Y||Journal of immunology (Baltimore, Md. : 1950) (162:2725)||1999|
Surface antigen expression in spleen cells of C57B1/6 mice during ageing: influence of sex and parity.
MA5-17748 was used in flow cytometry to test if pregnancies and gender influence the cellar changes observed during ageing in mice.
|Barrat F,Lesourd BM,Louise A,Boulouis HJ,Vincent-Naulleau S,Thibault D,Sanaa M,Neway T,Pilet CH||Clinical and experimental immunology (107:593)||1997|
Isolation of the most immature population of murine fetal thymocytes that includes progenitors capable of generating T, B, and myeloid cells.
MA5-17748 was used in flow cytometry to report that FcR is a useful marker to isolate the most immature population of murine fetal thymic cells.
|Hattori N,Kawamoto H,Katsura Y||The Journal of experimental medicine (184:1901)||1996|
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.
MA5-17748 was used in flow cytometry to report that TAN1 is an oncoprotein.
|Pear WS,Aster JC,Scott ML,Hasserjian RP,Soffer B,Sklar J,Baltimore D||The Journal of experimental medicine (183:2283)||1996|
Effects of the lpr mutation on elimination and inactivation of self-reactive B cells.
MA5-17748 was used in flow cytometry to investigate the fate of autoreactive B cells in lpr/lpr mice.
|Rathmell JC,Goodnow CC||Journal of immunology (Baltimore, Md. : 1950) (153:2831)||1994|