|Tested species reactivity||Mouse|
|Published species reactivity||Mouse, Not Applicable|
|Host / Isotype||Mouse / IgG2b|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1.0 ug/10^6 cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17750 targets CD90/Thy-1 in FACS applications and shows reactivity with Mouse samples.
The MA5-17750 immunogen is cBA/J.
Thy-1 or CD90 is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of Thy-1 lead to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
B-lymphocyte depletion ameliorates Sjögren's syndrome in Id3 knockout mice.
MA5-17750 was used in flow cytometry to investigate the role of B cells in Sjogren's syndrome in a mouse model
|Hayakawa I,Tedder TF,Zhuang Y||Immunology (122:73)||2007|
Immature multipotent hemopoietic progenitors lacking long-term bone marrow-reconstituting activity in the aorta-gonad-mesonephros region of murine day 10 fetuses.
MA5-17750 was used in flow cytometry to examine multipotent progenitors from early fetuses.
|Ohmura K,Kawamoto H,Lu M,Ikawa T,Ozaki S,Nakao K,Katsura Y||Journal of immunology (Baltimore, Md. : 1950) (166:3290)||2001|
Commitment of common T/Natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay.
MA5-17750 was used in flow cytometry to describe a clonal system that supports the development of T and natural killer cells evenly.
|Ikawa T,Kawamoto H,Fujimoto S,Katsura Y||The Journal of experimental medicine (190:1617)||1999|
Emergence of T, B, and myeloid lineage-committed as well as multipotent hemopoietic progenitors in the aorta-gonad-mesonephros region of day 10 fetuses of the mouse.
MA5-17750 was used in flow cytometry to investigate the aorta-gonad-mesonephros region as a source of hemopoietic progenitors.
|Ohmura K,Kawamoto H,Fujimoto S,Ozaki S,Nakao K,Katsura Y||Journal of immunology (Baltimore, Md. : 1950) (163:4788)||1999|