|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 372 and 586 of Human CDC2L5|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27702 targets CDC2L5 in WB applications and shows reactivity with Human samples.
The PA5-27702 immunogen is recombinant protein fragment corresponding to a region within amino acids 372 and 586 of Human CDC2L5.
The protein encoded by this gene is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. Some of the cell cycle control kinases are able to phosphorylate proteins that are important for cell differentiation and apoptosis, thus provide connections between cell proliferation, differentiation, and apoptosis. Proteins of this family may also be involved in non-cell cycle-related functions, such as neurocytoskeleton dynamics. The exact function of this protein has not yet been determined. It has unusually large N- and C-termini and is ubiquitously expressed in many tissues. Two alternatively spliced variants are described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDC2-related protein kinase 5; CDC2L; CDC2L5; Cell division cycle 2-like protein kinase 5; Cell division protein kinase 13; CHED; Cholinesterase-related cell division controller; Cyclin-dependent kinase 13; hCDK13
Gene Aliases: CDC2L; CDC2L5; CDK13; CHED; hCDK13; KIAA1791
UniProt ID: (Human) Q14004
Entrez Gene ID: (Human) 8621
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