Note: You clicked on an external link, which has been disabled in order to keep your shopping session open.
|Tested species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 187 of Human CDC42EP2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31049 targets CDC42EP2 in WB applications and shows reactivity with mouse samples.
The PA5-31049 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 187 of Human CDC42EP2.
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
binder of Rho GTPases 1; BORG1; cdc42 effector protein 2; CEP2; CRIB-containing BOGR1 protein
1110008C05Rik; Borg1; Cdc42ep2; Cep2; D19Bwg1013e