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This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1; Cdc7 Kinase; CDC7-like 1; CDC7-related kinase; cell division cycle 7 homolog; cell division cycle 7-like protein 1; Cell division cycle 7-related protein kinase; MGC117361; MGC126237; MGC126238; MGC91067
Gene Aliases: CDC7; CDC7L1; HsCDC7; Hsk1; huCDC7
UniProt ID: (Human) O00311
Entrez Gene ID: (Human) 8317
Molecular Function:
kinase
non-receptor serine/threonine protein kinase
protein kinase
transferase
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