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|Tested species reactivity||Human, Mouse, Non-human primate, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues surrounding Asp410 of human CDC73|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
It is not recommended to aliquot this antibody.
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cell division cycle 73 Paf1/RNA polymerase II complex component-like protein; cell division cycle 73, Paf1/RNA polymerase II complex component, homolog; Cell division cycle protein 73 homolog; hyperparathyroidism 2 (with jaw tumor); hyperparathyroidism 2 homolog; Hyperparathyroidism 2 protein; Hyperparathyroidism 2 protein homolog; Paf1/RNA polymerase II complex component; Parafibromin; Vcell division cycle 73, Paf1/RNA polymerase II complex component, homolog
8430414L16Rik; BC027756; C130030P16Rik; C1orf28; C81219; CDC73; FIHP; HPTJT; HRPT1; HRPT2; HYX