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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Extracellular domain of human cadherin-11 fused to maltose binding protein|
|Contains||0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Cadherin 11; cadherin 11, type 2, OB-cadherin (osteoblast); OB Cadherin; Osteoblast Cadherin
CAD11; CDH11; CDHOB; OB; OSF-4