|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant full-length human CDX2 protein|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
CDX2 is a member of caudal type homeo box family of transcription factor. CDX-2 is a permissive factor that influences basal CaBP expression in enterocytes; HNF-1alpha; modulates CaBP gene expression during cellular differentiation. CDX2, but not CDX1, interacts with the MUC2 promoter and activates MUC2 transcription, and plays an important role in the differentiation of goblet cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Association of hepatocyte-derived growth factor receptor/caudal type homeobox 2 co-expression with mucosal regeneration in active ulcerative colitis.
39-7800 was used in immunohistochemistry (paraffin) to determine the regeneration-associated stem cell-related phenotype of hepatocyte-derived growth factor receptor-expressing cells in active ulcerative colitis.
|Sipos F,Constantinovits M,Valcz G,Tulassay Z,M¿zes G||World journal of gastroenterology (21:8569)||2015|