Peptide Sequence: ASTLSDTKNM EIINSTIETL APDSPFDHKK TVSGFQKLEK LDPIAADQQD TVVFKVTEGK LLRDPLSHPG AEQTGIQNKT QMHPLMSQMS GS
This intronless gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chromodomain protein, Y chromosome, 2; Testis-specific chromodomain protein Y 2; Y chromosome chromodomain protein 2A
Gene Aliases: CDY; CDY2; CDY2A; CDY2B
UniProt ID: (Human) Q9Y6F7
Entrez Gene ID: (Human) 9426