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|Tested species reactivity||Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Peptide corresponding to amino acid residues from the N-terminal region of mouse C/EBP b protein|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||5 ug/ml|
|Western Blot (WB)||2 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Tissue specificity: Expressed at low levels in the lung, kidney and spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AGP/EBP; C/EBP BETA; CCAAT/enhancer-binding protein beta; CEBPB; interleukin-6-dependent-binding protein; LIP; liver-enriched transcriptional activator; nuclear protein Il6; TCF-5; TCF5
C/EBPbeta; Cebpb; CRP2; IL-6DBP; LAP; LIP; NF-IL6; NF-M; Nfil6