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NeoBiotechnologies
CELA3A/Chymotrypsin like elastase 3A Monoclonal Antibody (CELA3A/12552)
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FIGURE: 1 / 3
CELA3A/Chymotrypsin like elastase 3A Antibody (10136-MSM2-P1) in IHC (P)
Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human pancreas stained with CELA3A Mouse Monoclonal Antibody (CELA3A/12552). Inset: PBS instead of primary antibody; secondary only negative control.
Product Details
10136-MSM2-P1
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
CELA3A/12552
Immunogen
Recombinant fragment (around aa 50-250) of human CELA3A protein (exact sequence is proprietary).
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein G
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chymotrypsin-like elastase family member 3A; chymotrypsin-like elastase family, member 3A; elastase 1; elastase 3A, pancreatic; Elastase IIIA; Elastase-3A; Protease E
Gene Aliases: CELA3A; ELA3; ELA3A
UniProt ID: (Human) P09093
Entrez Gene ID: (Human) 10136
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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