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Product Details
H00009350-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CER1 (AAH69491.1, 1 a.a. approximately 267 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MHLLLFQLLV LLPLGKTTRH QDGRQNQSSL SPVLLPRNQR ELPTGNHEEA EEKPDLFVAV PHLVGTSPAG EGQRQREKML SRFGRFWKKP EREMHPSRDS DSEPFPPGTQ SLIQPIDGMK MEKSPLREEA KKFWHHFMFR KTPASQGVIL PIKSHEVHWE TCRTVPFSQT ITHEGCEKVV VQNNLCFGKC GSVHFPGAAQ HSHTSCSHCL PAKFTTMHLP LNCTELSSVI KVVMLVEECQ CKVKTEHEDG HILHAGSQDS FIPGVSA
Target Information
This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein antagonists that can bind directly to BMPs and inhibit their activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cer-l; Cerberus; cerberus 1, cysteine knot superfamily, homolog; cerberus homolog; Cerberus-like protein; cerberus-related 1; Cerberus-related protein; DAN domain family member 4; MGC119894; MGC119895; MGC96951
Gene Aliases: cer-1; CER1; Cerl; Cerl1; Cerr1; DAND4
UniProt ID: (Human) O95813, (Mouse) O55233
Entrez Gene ID: (Human) 9350, (Mouse) 12622
ureteric bud development
growth plate cartilage chondrocyte proliferation
gastrulation
nervous system development
negative regulation of cell proliferation
anterior/posterior axis specification
anterior/posterior pattern specification
signal transduction involved in regulation of gene expression
negative regulation of Wnt signaling pathway
bone mineralization
BMP signaling pathway
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
sequestering of BMP in extracellular matrix
cell migration involved in gastrulation
determination of dorsal identity
determination of heart left/right asymmetry
cellular response to BMP stimulus
negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
negative regulation of mesoderm development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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