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Product Details
MA5-30222
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
034
Immunogen
Recombinant Human CER1/Cerberus 1 Protein (Met1-Ala267)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2785982
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human CER1/Cerberus 1.
Target Information
This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein antagonists that can bind directly to BMPs and inhibit their activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cerberus; cerberus 1, cysteine knot superfamily, homolog; cerberus-related 1; Cerberus-related protein; DAN domain family member 4; MGC119894; MGC119895; MGC96951
Gene Aliases: CER1; DAND4
UniProt ID: (Human) O95813
Entrez Gene ID: (Human) 9350
ureteric bud development
growth plate cartilage chondrocyte proliferation
gastrulation
nervous system development
negative regulation of cell proliferation
anterior/posterior axis specification
anterior/posterior pattern specification
signal transduction involved in regulation of gene expression
negative regulation of Wnt signaling pathway
bone mineralization
BMP signaling pathway
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
sequestering of BMP in extracellular matrix
cell migration involved in gastrulation
determination of dorsal identity
determination of heart left/right asymmetry
cellular response to BMP stimulus
negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
negative regulation of mesoderm development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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