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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 18 and 233 of Human CFHL1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31232 targets CFHL1 in IF and WB applications and shows reactivity with Human samples.
The PA5-31232 immunogen is recombinant fragment corresponding to a region within amino acids 18 and 233 of Human CFHL1.
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CFHL; CFHL1; CFHL1P; CFHR1P; complement factor H-related 1 pseudogene; complement factor H-related protein 1; FHR-1; FHR1; H factor (complement)-like 1; H factor (complement)-like 2; h factor-like protein 1; H-factor-like 1; H36; H36-1; H36-2; HFL1; HFL2
CFHL; CFHL1; CFHL1P; CFHR1; CFHR1P; FHR1; H36-1; H36-2; HFL1; HFL2