ABS 026-05-02 detects CGRP alpha in human and rat samples. ABS 026-05-02 binds human alpha-CGRP. Based on inhibition ELISA, this antibody shows full cross-reactivity with rat alpha-CGRP and about about 50% cross-reactivity with human beta-CGRP. Cross-reactivity with coated rat alpha-CGRP is low (8%) and there is no cross-reaction with human amylin.
ABS 026-05-02 has been successfully used in ELISA and immunohistochemistry procedures.
ABS 026-05-02 immunogen is a synthetic peptide corresponding to residues 1-18 of human alpha-CGRP
Calcitonin gene-related peptide is a 37 amino-acid vasoactive neuropeptide (mw 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, in addition to a variety of other cellular effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha-type CGRP; Calcitonin; calcitonin 1; Calcitonin carboxyl-terminal peptide; Calcitonin gene-related peptide; Calcitonin gene-related peptide 1; Calcitonin gene-related peptide I; calcitonin-related polypeptide alpha; calcitonin/calcitonin-related polypeptide, alpha; CCP; CGRP-I; Katacalcin; PDN-21
Gene Aliases: Cal1; CAL6; Calc; CALC1; CALCA; calcitonin; CGRP; CGRP-I; CGRP1; CT; KC; PCT; RATCAL6