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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human CHGA (amino acids: 87-252 ) expressed in E. Coli.|
|Storage buffer||PBS with 0.5% proprietary stabilizer|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500 - 1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17056 targets CHGA in pep-ELISA and WB applications and shows reactivity with Human and Mouse samples.
The MA5-17056 immunogen is purified recombinant fragment of human CHGA (amino acids: 87-252 ) expressed in E. Coli.
MA5-17056 detects CHGA which has a predicted molecular weight of approximately 50.7kDa.
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
betagranin (N-terminal fragment of chromogranin A); catestatin; cgA; chromofungin; chromogranin-A; parathyroid secretory protein 1; pituitary secretory protein I; SP-I
CGA; CHGA; ChrA